中国实用神经疾病杂志2017，Vol.20Issue(11)：18-21,4.
阿司匹林对脑室旁脑白质疏松患者新发脑卒中的影响
Effect of aspirin on the prevention of stroke in patients with periventricular leukoaraiosis
摘要
Abstract
Objective To investigate the effect of aspirin on the prevention of stroke in patients with periventricular leukoaraiosis.Methods Four hundred lacunar infarction patients with periventricular leukoaraiosis were randomly divided into the treatment group (200 cases,aspirin) and the control group.The cases in the treatment group received aspirin 100 mg daily for 1 year,and patients in control group didn't take antiplatelet or anticoagulant drugs.All cerebrovascular events occurred in patients prescribed in one year.In all participants we measured the score of the Montreal Cognitive Assessment,the severity of periventricular leukoaraiosis and the number of cerebral microbleeds at the begining and the ending of this trial.Results The numbers of cerebral microbleeds in the treatment group were significantly higher than those in the control group.The incidence of acute cerebral infarction in the treatment group was significantly lower than that in the control group.There were no significant differences in the the incidence of acute cerebral hemorrhage,the score of the Montreal Cognitive Assessment and the severity of periventricular leukoaraiosis between two groups.Conclusion Among lacunar infarction patients with periventricular leukoaraiosis,aspirin can reduce the risk of acute cerebral infarction and has no side effect.关键词
脑白质疏松/阿司匹林/脑出血Key words
Leukoaraiosis/Aspirin/Cerebral hemorrhage分类
医药卫生引用本文复制引用
童慧,林福军,姜爱钟,周畅,胡婷婷..阿司匹林对脑室旁脑白质疏松患者新发脑卒中的影响[J].中国实用神经疾病杂志,2017,20(11):18-21,4.基金项目
2013南京市医学科技发展课题(编号YKK13221) （编号YKK13221）
