检验医学与临床2017，Vol.14Issue(10)：1377-1378,1381,3.DOI:10.3969/j.issn.1672-9455.2017.10.006
血浆FIB及D-二聚体在肺栓塞治疗中的临床意义
Clinical significance of plasma FIB and D-dimer in the treatment of patients with pulmonary embolism
钱蓓蓓 1张静华 2陶佳莹 1毛佩敏1
作者信息
- 1. 复旦大学附属妇产科医院输血科,上海 200090
- 2. 上海市第十人民医院检验科 200072
- 折叠
摘要
Abstract
Objective To investigate the clinical significance of plasma fibrinogen (FIB) and D-dimer (D-D) in the treatment of patients with pulmonary embolism.Methods A total of 65 cases admitted to Shanghai Tenth People′s Hospital with the diagnosis of pulmonary embolism were selected as pulmonary embolism group,89 cases of healthy people were selected as control group.In addition,patients with pulmonary embolism who were followed up for two years and the disease recurrence (19 cases) were selected as recurrence group,and the patients without recurrence (46 cases) were selected as non-recurrence group.The plasma FIB and D-D levels were compared between the groups,and the ROC curve was used to evaluate the FIB and D-D in the diagnosis of pulmonary embolism diagnosis value,as well as the in the prognosis of the recurrence group and non-recurrence group.Results The level of FIB and D-D in the pulmonary embolism group were significantly higher that that in the control group (P<0.05).ROC curves analysis showed than the area under the ROC curve of FIB for the diagnosis of pulmonary embolism was 0.937(P<0.05),and the area under the ROC curve of D-D for the diagnosis of pulmonary embolism was 0.981(P<0.05).The levels of FIB and D-D in patients with pulmonary embolism recurrence were significantly higher than that in the non-recurrence group(P<0.05).The area under the ROC of FIB and D-D for the prognosis of pulmonary embolism were 0.816 and 0.721,respectively(P<0.05).Conclusion Plasma FIB and D-D in the diagnosis and treatment of pulmonary embolism in patients with pulmonary embolism have higher accuracy,which also have the higher value in the prognosis of patients with pulmonary embolism.关键词
纤维蛋白原/D-二聚体/肺栓塞/治疗价值Key words
fibrinogen/D-dimer/pulmonary embolism/therapeutic value引用本文复制引用
钱蓓蓓,张静华,陶佳莹,毛佩敏..血浆FIB及D-二聚体在肺栓塞治疗中的临床意义[J].检验医学与临床,2017,14(10):1377-1378,1381,3.
