摘要
Abstract
Objective To discuss the expression and variation tendencies of cerebrospinal fluid cystatin C (Cys C) and mpt in nerve system diseases.Methods A total of 204 patients undergoing multiple cerebrospinal fluid biochemical marker detections,including the expression levels of cerebrospinal fluid Cys C and mpt in 14 kinds of diseases were analyzed before and after treatment,the differences in concentrations as well as variation tendency between Cys C and mpt were compared before and after treatment,and their expression modes in different disease groups were analyzed independently and jointly.Results Cerebrospinal fluid mpt generally decreased,while the proportion of patients in the lower interval of Cys C generally tended to gradually increase,and which decreased in a higher level interval.The variation tendency of Cys C concentration and those of different regions were independent from that of mpt,while both the initial level intervals of Cys C and mpt were correlated with the distribution intervals after treatment.The variation tendencies of Cys C and mpt concentrations before and after treatment showed no correlation with disease groups,and the migration tendency of Cys C after divisional treatment was not correlated with disease groups,while the migration tendency of mpt after divisional treatment was associated with disease groups.Through,a joint observation of Cys C and mpt could be seen that the testing results of Cys C and mpt in the joint divisional group were correlated with disease groups before and after treatment,and the joint variation tendency of Cys C and mpt distribution intervals were correlated with disease groups.Conclusion The expression levels and variation tendencies of cerebrospinal fluid Cys C before and after treatment are different from mpt,and the variation tendency still have differential expressions before and after treatment.The single use of spinal fluid Cys C is still limited,but its combination with mpt may play a positive role in the diagnosis and treatment monitoring of nerve system diseases.关键词
脑脊液/胱氨酸蛋白酶抑制剂C/脑脊液蛋白/神经系统疾病/动态表达/趋势分析Key words
cerebrospinal fluid/Cystatin C/total protein/nerve system diseases/dynamic expressions/variation tendencies
