检验医学与临床2017，Vol.14Issue(10)：1451-1452,1455,3.DOI:10.3969/j.issn.1672-9455.2017.10.033
胆石症合并胆道感染患者的病原菌分布及耐药性分析
Pathogens distribution and antibiotic resistance in patients with cholelithiasis complicated with biliary infection
李平 1康继莲1
作者信息
- 1. 重庆市荣昌区人民医院外二科 402460
- 折叠
摘要
Abstract
Objective To investigate the pathogens distribution and antibiotic resistance in patients with cholelithiasis complicated with biliary infection(CBI),so as to provide some guidance for reasonable clinical use of antibiotics.Methods A total of 180 patients with CBI were enrolled in the study.The bile samples were collected from these patients during the operations.Then the isolation and identification of pathogens and antibiotics susceptibility were tested.Results A total of 132 bacterial strains were isolated,including 98 strains of gram-negative bacteria(74.24%),31 strains of gram-positive bacteria(23.49%) and three fungal strains(2.27%).The top six kinds of strains were as following:Escherichia coli,51 strains(38.64%);Enterococcus,23 strains(17.43%);Klebsiella pneumonia,22 strains(16.67%);Enterobacter cloacae,14 strains(10.60%);Pseudomonas aeruginosa,7 strains(5.30%) and Staphylococcus had 7 strains(5.30%),respectively.None of the main Gram-negative strains resisted to imipenem.Escherichia coli and Klebsiella pneumonia strains showed a lower resistance to cefoperazone/sulbactam and amikacin while Enterobacter cloacae showed a lower resistance to amikacin.The main gram-positive strains showed a high susceptibility to vancomycin and linezolid,and a lower resistance to gentamycin.Besides,none of Staphylococcus strains resisted to levofloxacin.Conclusion The pathogens in CBI patients are generally resistant to the commonly used antibiotics.Antibiotics should be used reasonably basing on the results of the drug susceptibility testing.关键词
胆石症/胆道感染/病原菌/抗菌药物/耐药性Key words
cholelithiasis/biliary infection/pathogen/antibiotic drug/resistence引用本文复制引用
李平,康继莲..胆石症合并胆道感染患者的病原菌分布及耐药性分析[J].检验医学与临床,2017,14(10):1451-1452,1455,3.
