昆明医科大学学报2017，Vol.38Issue(1)：95-98,4.
肝动脉化疗栓塞联合调强放疗治疗原发性肝癌的临床疗效
Clinical Analysis of Transcatheter Arterial Chemoembolization Combined with Intensity Modulated Radiotherapy Therapy for Patients with Primary Hepatic Carcinoma
摘要
Abstract
Objective To evaluate the efficacy of transcatheter arterial chemoembolization (TACE) in combination with intensity modulated radiotherapy (IMRT) in treatment of primary hepatic carcinoma (PHC).Methods All 68 patients with PHC were randomized into treatment group (TACE plus IMRT) and control group (TACE alone),with 34 cases in each group.Patients in the control group were treated with interventional therapy alone.Patients in the treatment group were treated with interventional therapy (transcatheter arterial chemoembolization) plus radiotherapy.Treatment group patients firstly received 2 to 3 times interventional therapy,then followed by radiotherapy with 2 to 4 week interval.Results The short-term efficacy was 82.4％ in treatment group which was significantly higher than 61.8％ in control group (P＜0.05).The survival rate was 76.5％ in 1 year and 55.9％ in 2 years in treatment group,58.9％ and 32.4％ in control group respectively.The difference between 2 group was statistical significance (P＜0.05) No serious toxicities were observes in the patients of the two groups.Conclusion The results suggest that the treatment effect of TACE plus IMRT is better than interventional therapy alone for patients with primary Hepatic carcinoma,and has well tolerance and fewer adverse reactions.关键词
原发性肝癌/放射疗法/介入疗法/肝动脉化疗栓塞/调强放射治疗Key words
Primary hepatic carcinoma (PHC)/Radiotherapy/Interventional therapy/Transcatheter arterial chemoembolization (TACE)/Intensity modulated radiotherapy (IMRT)分类
医药卫生引用本文复制引用
高靖琰,陈富坤,鄢佳文,王家平..肝动脉化疗栓塞联合调强放疗治疗原发性肝癌的临床疗效[J].昆明医科大学学报,2017,38(1):95-98,4.基金项目
云南省科技厅应用基础研究基金资助项目(2009ZC111M) （2009ZC111M）
云南省教育厅科学研究基金资助项目(09Z0034) （09Z0034）
