世界中医药2017，Vol.12Issue(5)：1090-1093,4.DOI:10.3969/j.issn.1673-7202.2017.05.035
益心舒胶囊治疗2型糖尿病合并冠心病心绞痛的临床疗效分析
Analysis on Yixingshu Capsule in Treatment of Type 2 Diabetes Mellitus Complicated with Angina Pectoris due to Coronary Heart Disease
摘要
Abstract
Objective: To study the clinical analysis of Yixingshu capsule in treatment of type 2 diabetes mellitus complicated with angina pectoris due to coronary heart disease.Methods: A total of 88 patients with type 2 diabetes mellitus complicated with angina pectoris due to coronary heart disease were randomly divided into control group and observation group, 44 cases in each group.The control group was treated with conventional anti-angina pectoris and hypoglycemic agent, the observation group was treated with Yixinshu Capsule on basis of the control group, both for 8 weeks.After treatment, the clinical efficacy of the two groups was measured.The levels of blood glucose, blood lipid and platelet activation were measured before and after treatment.Results: The clinical symptoms, the effective rate of ECG and symptom improvement of the observation group were significantly increased compared with the control group and the proportion of ineffectiveness was significantly decreased (P<0.05 or P<0.01).The levels of FBG, 2 h PBG, HbA1c, TG, TC and LDL-C in the two groups were significantly decreased, and the observation group were significantly lower than those in the control group (P<0.05 or P<0.01).The level of HDL-C in the two groups were significantly increased and the observation group was significantly higher than the control group (P<0.01).The levels of PAC-1 and MAR were significantly increased compared with those before the treatment in the control group (P<0.05).The levels of LAP, CD62P, PAC-1 and MAR in the observation group were significantly decreased, and significantly lower than those in the control group (P<0.01).Conclusion: Yixinshu Capsule can significantly improve blood glucose and blood lipid and inhibit platelet activation of patients with type 2 diabetes mellitus complicated with coronary heart disease angina pectoris, improving clinical curative effect.关键词
2型糖尿病/冠心病心绞痛/益心舒胶囊/血糖/血脂/血小板活化/疗效Key words
Type 2 diabetes mellitus/Angina pectoris due to coronary heart disease/Yixinshu Capsule/Blood glucose/Blood lipid/Platelet activation/Efficacy分类
医药卫生引用本文复制引用
王前,高建步..益心舒胶囊治疗2型糖尿病合并冠心病心绞痛的临床疗效分析[J].世界中医药,2017,12(5):1090-1093,4.基金项目
河南省医学科技攻关计划项目(编号:201204149) （编号:201204149）
