生命科学研究2017,Vol.21Issue(2):166-173,8.DOI:10.16605/j.cnki.1007-7847.2017.02.013
氢气作为新型治疗气体的研究进展
Progresses on Molecular Hydrogen as Novel Therapeutic Gas
摘要
Abstract
Oxidative stress is the common pathological basis of most diseases.Molecular hydrogen (H2) acts as a therapeutic antioxidant by selectively reducing highly active oxidants-hydroxyl radical (· OH),and may be an important way of preventing and treating diseases.Currently,hundreds of human diseases could potentially be treated with molecular hydrogen.Medical studies on hydrogen have gradually become a hotspot and been carried out in cells,organs,animals and also in humans.However,the biological mechanisms related to hydrogen remain to be studied and explored in the future.Here,recent progresses are briefly reviewed toward biological effects,molecular mechanisms,intake methods and clinical applications of molecular hydrogen.关键词
氧化应激/抗氧化物质/氢气(H2)/分子机制/临床应用Key words
oxidative stress/antioxidant/hydrogen (H2)/molecular mechanisms/clinical application分类
医药卫生引用本文复制引用
韩世谦,叶治家..氢气作为新型治疗气体的研究进展[J].生命科学研究,2017,21(2):166-173,8.基金项目
国家自然科学基金资助项目(81170471,31371913) (81170471,31371913)
重庆市自然科学基金重点项目(csct2013jjB0190) (csct2013jjB0190)
第三军医大学军事医学预研基金资助项目(2014XJY03) (2014XJY03)