摘要
Abstract
Objective Analyze the prevalence situation of Diabetic Peripheral Neuropathy in type 2 diabetes mellitus,study the related risk factors and inflammatory factors.Methods From January 2015 to July 2016,according to DPN diagnostic criteria,the patients were diagnosed as type 2 diabeteswere divided into diabetic peripheral neuropathy group and non group.Respectively,check whether combined with diabetic retinopathy and peripheral vascular disease,then analysis of age,weight,BMI,course of disease,biochemical indicator,meanwhile,analyse single factor of each index,and then Logistic multivariate analysis.Results (1) The prevalence of diabetic peripheral neuropathy in the study population was 65.9％;(2)The number of combined with peripheral vascular disease in the diabetic peripheral neuropathy group(69％) was significantly higher than that in non diabetic peripheral neuropathy group (50％),through the x2 test,the difference was statistically significant (x2 =5.723,P ＜ 0.05);(3) compared with non group,in the analysis of various factors,the HbA1 c、LDL-C、IL-6 、TNF-α、SIL-2R and disease course of diabetic peripheral neuropathy group was statistically significant (t =2.084 ～ 3.407,P ＜ 0.05).But there was no statistically significant difference compared to other factgrs.(4) Logistic multivariate analysis:Course 、HbA1 c 、LDL-C、TNF-α、SIR-2R and combined with peripheral vascular disease are independent risk factors for DPN (OR =0.455 ～ 1.655,P ＜ 0.05).Conclusions The extension of the disease course,peripheral vascular disease,and blood glucose,blood lipid levels and related inflammatory factors of abnormal,will make diabetic neuropathy exacerbations.关键词
2型糖尿病/糖尿病周围神经病变/危险因素/炎性反应因子Key words
type 2 diabetes mellitus/diabetic peripheral neuropathy/risk factors/inflammatory factors分类
医药卫生
