中国组织工程研究2017，Vol.21Issue(14)：2147-2152,6.DOI:10.3969/j.issn.2095-4344.2017.14.003
不同方式灌注骨水泥治疗骨质疏松性椎体压缩骨折的比较
Different bone cement implantation ways for osteoporotic vertebral compression fractures
摘要
Abstract
BACKGROUND: After the treatment of osteoporotic vertebral compression fractures with bone cement implantation,deteriorative osteoporosis and the distance augment between bone cement and bones result in a decrease in bone cement-bone interface compression strength and torsion strength, and then the bone cement tends to displace, which is easy to cause a secondary vertebral fracture.OBJECTIVE: To investigate the clinical efficacy of bone cement implantation via three approaches on osteoporotic vertebral compression fractures.METHODS: Sixty patients with single osteoporotic vertebral compression fracture were treated with vertebroplasty,percutaneous kyphoplasty or fraction cement vertebroplasty. All data were collected to analyze the correlation between the bone cement morphology and treatment method, and to detect the visual analogue scale, Oswestry disability index,Cobb angle and incidence of secondary vertebral fractures.RESULTS AND CONCLUSION: The visual analogue scale scores, Oswestry disability index, and Cobb angle in thethree groups were significantly improved after treatment (P < 0.05). All above indicators showed no significant difference among groups at each time point after treatment, suggesting that these three kinds of treatments exert the same effects on pain relief, functional recovery, preventing the vertebral height loss and maintaining spinal mechanical properties.Bone cement displacement and secondary vertebral fracture occurred after clotted cement implantation. Therefore,mixed and trabecular-shaped grafts are preferred, aiming to achieve good long-term treatment outcomes in osteoporotic vertebral compression fractures.关键词
生物材料/骨生物材料/骨质疏松症/椎体压缩骨折/经皮椎体成形术/经皮椎体后凸成形术分类
医药卫生引用本文复制引用
周伟,刘贵省,周丽萍,高芳,刘训伟,谢志勇..不同方式灌注骨水泥治疗骨质疏松性椎体压缩骨折的比较[J].中国组织工程研究,2017,21(14):2147-2152,6.基金项目
国家高技术研究发展计划(863计划)资助(2013AA032203) Funding: the National High-Tech Research and Development Program of China (863 Program), No. 2013AA032203 （863计划）
