中国组织工程研究2017，Vol.21Issue(15)：2331-2335,5.DOI:10.3969/j.issn.2095-4344.2017.15.007
高血压对人工股骨头置换后伤口延迟愈合的影响
Impact of hypertension on delayed wound healing after femoral head replacement
摘要
Abstract
BACKGROUND: At present, most of the literature on joint replacement focus on the causes and countermeasures of long-term complications, but seldom focuses on causes of postoperative short-term complications, such as wound exudation and delayed union. Whether the incidence of sustained exudation and delayed wound healing in patients with hypertension after hip replacement is higher than that in patients with normal blood pressure is not reported at present.OBJECTIVE: To identify the correlation of hypertension with persistent wound exudation and delayed wound healing in patients after femoral head replacement.METHODS: Data of 205 elderly patients with femoral neck fractures were retrospectively analyzed. All patients underwent femoral head replacement. In accordance with the hypertension diagnostic criteria of 2010 Chinese Guidelines for the Management of Hypertension, patients were divided into hypertension group and control group.Intraoperative blood loss, postoperative blood loss, the days of prolonged wound exudation, the wound dehiscence, and the prevalence of delayed wound healing were compared between the two groups. Then, we analyzed the relationship of hypertension with wound exudation and delayed wound healing.RESULTS AND CONCLUSION: (1) The average systolic blood pressures were 153.55 mmHg and 128.82 mmHg in the hypertension and control groups, respectively (P < 0.05). (2) No significant difference in age, gender, MNA-SF score, diabetes, body mass index, intraoperative blood loss, and postoperative blood loss was found between the two groups (P > 0.05). (3) The time of persistent wound exudation was 4.03 days and 2.08 days in the hypertension group and control group, respectively (P < 0.05). (4) The prevalence of delayed wound healing was significantly higher in the hypertension group than that in the control group (P < 0.05). (5) Hypertensive patients had a higher risk of prolonged wound exudation and delayed healing than their normotensive counterparts, and the hypertension is one of the important influence factors for delayed wound healing.关键词
骨科植入物/人工假体/股骨颈骨折/人工股骨头置换/伤口渗出/伤口延迟愈合分类
医药卫生引用本文复制引用
刘国印,贾小宝,吴伟华,孙小草,顾洁琼,陈建民..高血压对人工股骨头置换后伤口延迟愈合的影响[J].中国组织工程研究,2017,21(15):2331-2335,5.基金项目
南京市科技计划项目(201503007) （201503007）
南京军区科技创新项目(15ZD020)the Science and Technology Plan Program of Nanjing City, No. 201503007 （15ZD020）
the Science and Technology Innovation Project of Nanjing Military Area, No. 15ZD020 （）
