中国组织工程研究2017，Vol.21Issue(15)：2336-2341,6.DOI:10.3969/j.issn.2095-4344.2017.15.008
小剂量不同浓度罗哌卡因麻醉在老年膝髋关节置换中的效果
Anesthetic effect of different concentrations of low-dose hypobaric ropivacaine in elderly knee or hip replacement
摘要
Abstract
BACKGROUND: Unilateral spinal epidural anesthesia with ropivacaine can reduce the perioperative pain in the elderly undergoing hip or knee arthroplasty, but choosing which concentration of small dose hypobaric ropivacaine is an issue of concern.OBJECTIVE: To explore the anesthetic and analgesic effects of unilateral spinal epidural anesthesia with different concentrations of low dose hypobaric ropivacaine in senile knee or hip replacement.METHODS: Ninety patients undergoing knee or hip replacement in the Henan Province Hospital of TCM from August 2014 to December 2015 were enrolled, and randomized into 0.15%, 0.5% and 0.25% ropivacaine groups (n=30 per group), followed by spinal epidural anesthesia at L3-4 or L2-3 lumbar interspace, respectively.RESULTS AND CONCLUSION: (1) The order of the flat subsided time and motor block recovery time was as follows:0.15% ropivacaine group < 0.25% ropivacaine group < 0.5% ropivacaine group; the onset time of motor block was longest in the 0.25% ropivacaine group, followed by 0.5% ropivacaine group, and shortest in the 0.15% ropivacaine group (all P < 0.05). (2) The order of the visual analogue scale scores at 1, 5, and 10 hours after anesthesia and 24 hours postoperatively was as follows: 0.5% ropivacaine group < 0.25% ropivacaine group < 0.15% ropivacaine group (P < 0.05). (3) The change levels of heart rate and blood pressure were highest in the 0.5% ropivacaine group, followed by 0.15% ropivacaine group, and lowest in the 0.25% ropivacaine group. (4) The incidence of adverse events was highest in the 0.5% ropivacaine group, followed by 0.15% ropivacaine group, and lowest in the 0.25% ropivacaine group (P < 0.05). (5) To conclude, 3 mL of 0.25% ropivacaine exhibits desired anesthetic effect.关键词
骨科植入物/人工假体/罗哌卡因/小剂量/轻比重/笔尖式腰穿针/腰-硬联合麻醉/老年膝髋关节置换/目测类比评分/麻醉镇痛效果分类
医药卫生引用本文复制引用
庞留成,赵峰,杨建生,赵彦芬..小剂量不同浓度罗哌卡因麻醉在老年膝髋关节置换中的效果[J].中国组织工程研究,2017,21(15):2336-2341,6.基金项目
河南省卫生厅科技攻关项目(A20140307)the Technologies Research and Development Program of Health Department of Henan Province,No. A20140307 （A20140307）
