中国组织工程研究2017，Vol.21Issue(15)：2342-2348,7.DOI:10.3969/j.issn.2095-4344.2017.05.009
跨伤椎椎弓根钉内固定合并同种异体骨椎体后外侧植骨修复胸腰椎爆裂性骨折
Pedicle screw fixation combined with posterior-lateral fusion with autogenous bone for thoracolumbar burst fractures
董友军 1吴亮 1吴国峰 1周剑 1王锟 1孙晗 1孙晓亮1
作者信息
- 1. 苏州大学附属第三医院骨科,江苏省常州市 213000
- 折叠
摘要
Abstract
BACKGROUND: Spinal reconstruction plays an important role in the treatment of thoracolumbar burst fractures, but wherther the vertebral fusion can effectively reduce the loss of correction still remains controversial. OBJECTIVE: To investigate the repair effect of pedicle screw fixation combined with posterior-lateral fusion with autogenous bone for thoracolumbar burst fractures.METHODS: Eighty patients with thoracolumbar burst fractures undergoing pedicle screw fixation from January 2011 to June 2015 were enrolled, and were then randomly divided into experimental (posterior-lateral fusion with autogenous bone) and control groups (n=40 per group). The clinical efficacy was assessed according to the operation time, intraoperative blood loss and postoperative drainage volume, wound scale scores, anterior vertebral height and Cobb angle, American Spinal Injury Association impairment scale, and Oswestry dysfunction index.RESULTS AND CONCLUSION: (1) All patients were followed up for 24 months. The operation time, intraoperative blood loss and postoperative drainage volum in the experimental group were significantly more than those in the control group (P < 0.05). (2) The anterior vertebral height and Cobb angle were significantly improved in both two groups (P < 0.01), and there was slight loss in vertebral height and Cobb angle in both two groups durring follow-up, but showed no significant difference between two groups (P > 0.05). (3) The American Spinal Injury Association impairment scale and Oswestry dysfunction index scores were significantly improved in the two groups, but had no significant difference between two groups (P > 0.05). (4) These results suggest that pedicle screw internal fixation is effective and safe for thoracolumbar burst fractures. Posterior-lateral fusion with autogenous bone allograft holds a good histocompatibility, but cannot reduce postoperative correction loss, therefore, it is not recommended for vertebral burst fractures.关键词
骨科植入物/脊柱植入物/同种异体骨/椎体后外侧植骨/椎弓根内固定系统/爆裂性骨折分类
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董友军,吴亮,吴国峰,周剑,王锟,孙晗,孙晓亮..跨伤椎椎弓根钉内固定合并同种异体骨椎体后外侧植骨修复胸腰椎爆裂性骨折[J].中国组织工程研究,2017,21(15):2342-2348,7.
