高度近视相关基因的研究进展
Recent advances in genetic study on high myopia
摘要
Abstract
High myopia is a common blinding eye disease with high specificity and population genetic heterogeneity.It has emerged as a major public health concern,which is often accompanied by many severe associated comorbidities,including retinal detachment,cataract and glaucoma.While rarely effective treatment Is found so far.This article reviews recent advances in understanding genetic mechanism of high myopia,such as mode of inheritance,MYP locus and candidate genes.关键词
高度近视/MYP基因位点/候选基因/遗传学进展Key words
high myopia/MYP loci/candidate gene/genetic advances分类
医药卫生引用本文复制引用
李少玉,蒋文君,毕宏生..高度近视相关基因的研究进展[J].眼科新进展,2017,37(5):488-491,4.基金项目
国家科技支撑计划项目(编号:2015BAI04B04) （编号:2015BAI04B04）
国家自然科学基金项目(编号:81603421) （编号:81603421）
山东自然科学基金(编号:ZR2014HQ024) （编号:ZR2014HQ024）
山东省科技发展计划和重点研发计划(编号:2014GGH219004、2015GSF118043、2016GGH3119) （编号:2014GGH219004、2015GSF118043、2016GGH3119）
山东省医药卫生科技发展计划(编号:2015WS0141) （编号:2015WS0141）
山东省中医药科技发展计划(编号:2015-148)National Science and Technology Support Program (No:2015BAI04B04) （编号:2015-148）
National Natural Science Foundation of China (No:81603421) （No:81603421）
National Natural Science Foundation of ShanDong(No:ZR2014HQ024) （No:ZR2014HQ024）
Shandong Province Science and Technology Development Plan and Key R & D Plan(No:2014GGH219004,2015GSF118043,2016GGH3119) （No:2014GGH219004,2015GSF118043,2016GGH3119）
Shandong Province medical and health technology development plan (No:2015WS0141) （No:2015WS0141）
Shandong science and technology development plan of traditional Chinese Medicine (No:2015-148) （No:2015-148）
