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中心组合设计-响应面法优化银杏活脑胶囊的提取工艺

漆立军 覃鸿恩 黄华斌

医药导报2017,Vol.36Issue(6):668-672,5.
医药导报2017,Vol.36Issue(6):668-672,5.DOI:10.3870/j.issn.1004-0781.2017.06.017

中心组合设计-响应面法优化银杏活脑胶囊的提取工艺

Extraction Process of Yinxing Huonao Capusle by Central Composite Design-Response Surface Method

漆立军 1覃鸿恩 1黄华斌1

作者信息

  • 1. 湖北省恩施土家族苗族自治州中心医院药学部,恩施 445000
  • 折叠

摘要

Abstract

Objective To explore the extraction process of Yinxing Huonao capusle.Methods Central composite design-response surface method was used to optimize the extraction process with quantity of water and boiling time as main factors and with syringin transfer rate,emodin transfer rate and solids retention rate as evaluation index.Results The conditions of the optimized extraction process were as follows:10-fold water,extracting time of 160 min,extracting 2 times.Conclusion It is feasible that central composite design-response surface method is used to optimize the extraction process of Yinxing Huonao capusle,and the optimized extraction process is simple and reliable.

关键词

银杏活脑胶囊/中心组合设计-响应面法/提取工艺

Key words

Yinxing Huonao capusle/Central composite design-response surface methodology/Extraction process

分类

医药卫生

引用本文复制引用

漆立军,覃鸿恩,黄华斌..中心组合设计-响应面法优化银杏活脑胶囊的提取工艺[J].医药导报,2017,36(6):668-672,5.

医药导报

OA北大核心CSTPCD

1004-0781

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