中华耳科学杂志2017,Vol.15Issue(2):147-152,6.DOI:10.3969/j.issn.1672-2922.2017.02.002
EMG修正对颈部及眼部前庭诱发肌源性电位的影响
Effects of EMG Rectification on Cervical and Ocular Vestibular Evoked Myogenic Potentials
摘要
Abstract
To study the influence of EMG rectification on cervical and ocular vestibular evoked myo-genic potentials, and to establish the normal range of cervical vestibular evoked myogenic potentials (cVEMP) and ocu-lar vestibular evoked myogenic potentials (oVEMP) for accurate assessment of vestibular receptor function. Twenty normal hearing adult volunteers (10 male and 10 female, 40 ears) without ear diseases, aged from 20 to 30 years (mean age=23.76 ± 2.81 years), were included in the study. cVEMPs and oVEMPs were induced using 500 Hz tone-bursts, delivered through ER-3A standard insert earphones at 100 dB nHL, while the subject assumed a sitting posi-tion. cVEMP and oVEMP responses with clear and repeatable waveforms were acquired in all subjects. The P1 and N1 latencies of cVEMPs were 14.13 ± 1.97 and 21.54 ± 2.23 ms, respectively, with an amplitude of 1.63 ± 0.60μV. oVEMP P1 and N1 latencies were 10.15±0.72 ms and 15.79±1.01 ms, respectively, with an amplitude of 1.38±1.02μV. EMG rectification of cVEMPs yielded amplitude differences of 40-50 times (P<0.05). Has a significant effect on amplitude normalization, especially for cVEMPs. Establishment of normal VEMP amplitude range with EMG rectification can improved the accuracy in the assessment of response asymmetry. The high response rate of tone-burst evoked VEMPs in a sitting position makes this test a valuable tool in vestibular evaluation, not only for assessment of utricular and saccular functions, but also for differential diagnosis.关键词
颈部前庭诱发肌源性电位/眼部前庭诱发肌源性电位/振幅标准化/肌电图修正Key words
cVEMP/oVEMP/Amplitude Normalization/EMG Rectification分类
医药卫生引用本文复制引用
于澜,吴子明,冀飞,赵立东,王秋菊,赵苗苗,李清溪,刘兴健,谌国会,熊芬,谢林怡,兰兰,王大勇..EMG修正对颈部及眼部前庭诱发肌源性电位的影响[J].中华耳科学杂志,2017,15(2):147-152,6.基金项目
本研究由国家重大科学研究计划项目(2014CB943001),国家自然科学基金重点项目(81530032)和中国博士后科学基金面上项目(2015M572766)联合资助. Funding:This work was supported by grants of the National Key Basic Research Program of China (No. 2014CB943001), the Na-tional Natural Science Foundation of China (No. 81530032) and China Postdoctoral Science Foundation (No. 2015M572766). (2014CB943001)