中华耳科学杂志2017，Vol.15Issue(2)：168-173,6.DOI:10.3969/j.issn.1672-2922.2017.02.006
突聋伴眩晕患者前庭诱发肌源性电位的临床研究
Vestibular evoked myogenic potentials in patients with sudden deafness and vertigo
摘要
Abstract
Objective To report response rates and characteristics of vestibular evoked myogenic potentials in pa-tients with sudden deafness and vertigo and discuss the diagnostic and prognostic values of vestibular evoked myogenic potentials. Methods Fifty cases of unilateral sudden deafness with vertigo were included in the study group, while 60 normal subjects and 50 cases of unilateral sudden deafness without vertigo were included as the control. oVEMPs and cVEMPs were compared between patients and normal subjects. Results The rate of positive oVEMPs was 24%in the af-fected ear and 42%in the contralateral ear in patients with sudden deafness and vertigo, 48%in the affected ear in pa-tients with sudden deafness but no vertigo, and 100%in normal subjects;while the rate of positive cVEMPs was 56%in the affected ear and 74%in the contralateral ear in patients with sudden deafness and vertigo, 64%in the affected ear in patients with sudden deafness and no vertigo, and 100%in normal subjects. There were no significant differences be-tween the affected and contralateral ears (P>0.05). Compared to normal subjects, oVEMPs and cVEMPs in both the af-fected and contralateral ears were significantly reduced (P<0.05). The rate of positive oVEMPs in the affected ear was significantly lower in patients with sudden deafness and vertigo than in those patients with sudden deafness but no verti-go (P<0.05). oVEMP parameters (N1 latency, P1 latency, amplitudes) and asymmetry ratio (AR) were not significantly different among the groups (P>0.05). cVEMP N1-P1 amplitudes in the affected ear in patients with both sudden deaf-ness and vertigo were significantly lower than in patients with sudden deafness but no vertigo and normal subjects (P<0.05). The asymmetry ratio (AR) was also different when compared between patients with sudden deafness and vertigo and the normal subjects (P<0.05). oVEMPs, cVEMPs, patterns of audiogram and the degree of hearing loss showed no obvious correlations (P>0.05). However, oVEMPs and cVEMPs appeared to be correlated with therapeutic effects (P<0.05). Conclusions The utricle (superior vestibular nerve) and saccule (inferior vestibular nerves) on both sides may be dysfunctional in patients suffering from sudden deafness with vertigo. The dysfunction and its prognosis may be moni-tored objectively by VEMP examinations.关键词
前庭诱发肌源性电位/突聋伴眩晕/椭圆囊/球囊Key words
vestibular evoked myogenic potential/sudden deafness with vertigo/utricle/saccule分类
医药卫生引用本文复制引用
邢英姿,裴建军,赵姝,李淑静,刘雅静,李立群,侯庆军,王东海,路虹..突聋伴眩晕患者前庭诱发肌源性电位的临床研究[J].中华耳科学杂志,2017,15(2):168-173,6.基金项目
2017年度河北省医学科学研究重点课题计划,项目编号:20171308 （）
Fund projects: 2017 key project of medical scientific research in Hebei province (20171308). Declaration of interest:The authors report no conflicts of interest. （20171308）
