中华耳科学杂志2017，Vol.15Issue(2)：185-190,6.DOI:10.3969/j.issn.1672-2922.2017.02.009
隐性听力损失的发病机制及听力学表现
Pathogenesis and audiologic performances in hidden hearing loss
摘要
Abstract
Hidden hearing loss is a suprathreshold auditory perceptual deficits which only manifests as deteriorat-ing speech recognition in noise, and is usually not identified by routine clinical hearing threshold tests and thus often un-detected. This article describes the pathogenesis and auditory performance in hidden hearing loss, focusing on impair-ment of three important parts of the cochlear afferent pathway, i.e. synapses between outer and inner hair cells and spiral ganglion cells and postsynaptic afferent pathways;cochlear glutamate-glutamine cycles;and the cochlear efferent sys-tem, including lateral olivocochlear bundles and cochlear afferent synaptic complex formation of the third synaptic and medial olivocochlear bundles, in order to provide an evidence based basis for early diagnosis of hidden hearing loss, and theoretical and experimental bases for early intervention in hidden hearing loss.关键词
隐性听力损失/谷氨酸-谷氨酰胺循环/耳蜗传入突触复合体Key words
Hidden hearing loss/glutamic acid-glutamine cycle/Cochlear afferent synaptic complex分类
医药卫生引用本文复制引用
李国庆,吕萍,王秋菊..隐性听力损失的发病机制及听力学表现[J].中华耳科学杂志,2017,15(2):185-190,6.基金项目
国家重大科学研究计划项目(2014CB943001) （2014CB943001）
国家自然科学基金重点项目(81530032) （81530032）
国家自然科学基金(81470700 H1304) （81470700 H1304）
四川省教育厅课题(16ZB0231) Fund project: National major scientific research project(2014CB943001) （16ZB0231）
National Natural Science Foundation of key projects (81530032) （81530032）
National Natural Science Foundation of China(81470700 H1304) （81470700 H1304）
Sichuan Provincial Education Department(16ZB0231) （16ZB0231）
