中成药2017，Vol.39Issue(5)：922-925,4.DOI:10.3969/j.issn.1001-1528.2017.05.008
三七化瘀口服液对外伤性股骨干闭合粉碎性骨折高危人群围术期的影响
Effects of Sanqi Huayu Oral Liquid on femoral shaft comminuted fracture caused by trauma in perioperative period of high-risk groups
摘要
Abstract
AIM To investigate the effects of Sanqi Huayu Oral Liquid (Notoginseng Radix et Rhizoma,Corydalis Rhizoma) on femoral shaft comminuted fracture caused by trauma in perioperative period of high-risk groups.METHODS One hundred and twenty patients meeting the inclusion criteria were randomly and equally divided into treatment group and control group.The control group was treated by low molecular weight heparin calcium injection,while the treatment group was additionally given Sanqi Huayu Oral Liquid.Two groups' levels of serum IL-6,TNF-α and D-D were detected on pre-operation and the 1 st,3rd,7th after operation,respectively.Additionally,the adverse drug reactions were also observed.RESULTS There were no statistically significant differences in the levels of serum IL-6,TNF-α and D-D between the two groups before operation.The first day after operation,the levels of serum IL-6,TNF-α and D-D between the two groups showed increasing trends,which had similar elevated levels without statistically significant differences.The third day after operation,the levels of serum IL-6,TNF-α and D-D between the two groups presented downward trends,but those in the treatment group were decreased more markedly with statistically significant differences.Furthermore,the seventh day after operation,the levels of serum IL-6,TNF-α and D-D between the two groups were lower than those before the operation,and these indices in the treatment group were lower than those in the control group with statistically significant differences.CONCLUSION Sanqi Huayu Oral Liquid can not only effectively reduce the levels of serum IL-6,TNF-α and D-D in perioperative period of high-risk groups,but also prevent the formation of deep vein thrombosis.关键词
三七化瘀口服液/外伤性股骨干闭合粉碎性骨折/高危人群/围术期/IL-6/TNF-α/D-DKey words
Sanqi Huayu Oral Liquid/femoral shaft comminuted fracture caused by trauma/high-risk groups/perioperative period/IL-6/TNF-α/D-D分类
医药卫生引用本文复制引用
黎清斌,张兆华,劳永锵,陈苑妮,梁伟春,王明爽,潘海文,赵崇智..三七化瘀口服液对外伤性股骨干闭合粉碎性骨折高危人群围术期的影响[J].中成药,2017,39(5):922-925,4.基金项目
佛山市医学类科技攻关立项课题(2014AB00323) （2014AB00323）
