辐射防护2017，Vol.37Issue(2)：131-137,7.
基于蒙特卡罗数学模型评价不同螺距冠状动脉CCTA受检者辐射剂量的特点与验证
Estimation and validation of radiation dose to patients subjected to high-pitch and standard-pitch CCTA using Monte Carlo software
摘要
Abstract
The distribution characteristics of radiation dose of Coronary Computed Tomography Angiography (CCTA) with high-pitch and standard-pitch is studied using Monte Carlo simulation.The data from 61 patients subjected to high-pitch CCTA using the dual source CT scanner were collected and divided into 3 groups according to the BMI classification for Asians recommended by WHO:normal group (12 cases),overweight group (41 cases) and obese group (8 cases).Organ dose and effective dose (E) of the three groups with high-pitch and standard-pitch CCTA were calculated using Monte Carlo software.In high-pitch mode,the effective dose values calculated by Monte Carlo software were compared with the direct data readings from the CT equipment.The results showed that the organ dose of high-pitch CCTA calculated by the Monte Carlo software was about 70％ lower than that of standard-pitch CCTA on the dual source spiral CT.The most significant reductions in organ doses were found for heart and thymus,which have decreased by about 80％.For all the 3 groups,the effective doses of high-pitch CCTA were significantly lower than those of the standard-pitch CCTA (p ＜0.05),and the most obvious reduction in E was found in patients of the normal group subjected to the high-pitch CCTA.In high-pitch mode,deviation in E between the Monte Carlo simulation and the reading of the CT device was less than 50％.This suggested that,as a new clinical calculation method for radiation dose,Monte Carlo simulation can be used for prediction or retrospective analysis of the distribution of organ dose and E in CCTA.It is also indicated that the chest organ dose and effective dose can be significantly reduced with the high-pitch CCTA,and this will subsequently decrease the radiation risk,especially for the subjects of smaller BMI (such as children).This study has a potential for practical applications in development of low dose CT technology.关键词
冠状动脉造影/双源CT/体层摄影术/数学模型/辐射剂量Key words
Coronary Computed Tomography Angiography (CCTA)/dual source computed tomography/computed tomography/mathematical model/radiation dose分类
能源科技引用本文复制引用
刘潇,曾勇明,郁仁强,王杰,孙静坤..基于蒙特卡罗数学模型评价不同螺距冠状动脉CCTA受检者辐射剂量的特点与验证[J].辐射防护,2017,37(2):131-137,7.基金项目
国家临床重点专科建设项目基金(国卫办[2013]544号) （国卫办[2013]544号）
重庆市卫生局科研基金(10-2-055). （10-2-055）
