口腔疾病防治2017，Vol.25Issue(5)：288-293,6.DOI:10.12016/j.issn.2096-1456.2017.05.003
不同粒径和形貌的羟基磷灰石对牙本质小管的堵塞作用及耐磨性研究
The blocking effect and abrasion resistance of hydroxyapatite with different particle sizes and morphologies for dentinal tubules
摘要
Abstract
Objective To study the blocking effect and abrasion resistance of hydroxyapatite (HA) with different particle sizes and morphologyies on dentinal tubules from the qualitative and quantitative aspects. Methods Dentin discs were etched and divided into 4 groups randomly: 20 nm HA group; 30 nm HA group; 12 μm HA group; control group (without any experimental treatment). Each group was brushed with correspondent materials for 7 days. Then, the dentin disk was divided into two parts, the one was detected by the scanning electron microscopy (SEM);the other was observed by SEM after toothbrush abrasion test. The Image-Pro Plus 6.0 image analysis software was used to calculate the plugging rate of dentinal tubules. Results SEM showed that the blockage is granular, the plugging rate of the den-tinal tubules were about 82%to 96%. 30 nm HA group (short rod) range the first in the average plugging rate, followed by the 20 nm HA group (needles) and 12μm HA group (spherical). After mechanical brushing for 7 days, SEM images showed that deposited layer in each group was smooth and compact, and more than 63% of the tubules still had been blocked. Conclusion HA with different particle sizes and morphologies had good plugging effect and abrasion resis-tance on dentine tubules. The blocking effect of HA was affected not only by particle size but also by the morphology.关键词
羟基磷灰石/牙本质过敏症/牙本质小管/纳米/脱矿Key words
Hydroxyapatite/Dentine hypersensitivity/Dentine tubules/Nano/Demineralization分类
医药卫生引用本文复制引用
杨剑珍,申晓青,刘成霞,徐平平..不同粒径和形貌的羟基磷灰石对牙本质小管的堵塞作用及耐磨性研究[J].口腔疾病防治,2017,25(5):288-293,6.基金项目
广东省自然科学基金(2014A030313330) （2014A030313330）
广州市科技计划项目(201707010199) （201707010199）
