中医药导报2017，Vol.23Issue(9)：59-61,65,4.
陕产大黄结合型蒽醌转化游离型蒽醌的发酵条件优化
Optimization of Fermentation Conditions for Conversion of Conjagated Anthraquionone into Free Anthraquionone in Dahuang(Radix et Rhizoma Rhei) from Shaanxi
摘要
Abstract
Objective:Conjagated anthraquioaxane is the main composition in Dahuang (Radix et Rhizoma Rhei).To study the Fermentation conditions for conversion of conjagated anthraquionone into free anthraquionone by orthogonal array design.Methods:Optimization by orthogonal array design based on free anthraquionone conversion rate,and desorption capacity were compared with different types of fermentation temperature,fermentation time,fluid volume,table speed.Results:The optimal conditions of fermentation the was fermentation temperature 35 ℃;fermentation time was 7 d;fluid volume was 50 mL;table speed was 140 rad/min;in these condition,the free anthraquionone conversion rate was 42.369％.Conclusion:Fermentation is an effective way to onversion of conjagated anthraquionone into free anthraquionone,and the side effect of severe diarrhea caused by Dahuang (Radix et Rh&oma Rhei) can be alleviated through fermentation processing by yeast.关键词
大黄/发酵/结合型蒽醌/游离型蒽醌Key words
Dahuang (Radix et Rhizoma Rhei)/frementation/conjagated anthraquionone/free anthraquionone分类
医药卫生引用本文复制引用
高洁,董文宾,王勇,王萍..陕产大黄结合型蒽醌转化游离型蒽醌的发酵条件优化[J].中医药导报,2017,23(9):59-61,65,4.基金项目
陕西省教育厅科研计划项目(12JK1044) （12JK1044）
陕西省咸阳市科技局科学技术研究项目(2015K04-20) （2015K04-20）
