解放军医学院学报2017，Vol.38Issue(5)：414-416,448,4.DOI:10.3969/j.issn.2095-5227.2017.05.007
叶黄素对白内障术后患者黄斑及视觉功能的影响
Effects of lutein on the macular and visual function after cataract surgery in the elderly
摘要
Abstract
Objective To explore the effects of lutein on the macular and visual function after cataract surgery in the elderly.Methods Total of 80 patients with senile cataract including 52 males and 28 females with an average age of 55-75 years old were selected and randomly divided into group A(experiment group, n=40, postoperatively treated with lutein, 12 mg/d, once a day for 3 months) and group B (control group, n=40, postoperatively treated with starch as placebo, 12 mg/d, once a day for 3 months). All the patients underwent phacoemulsification plus intraocular lens implantation before the experiment. At T0 (before experiment), T1 (1 month after experiment), T2 (3 months), T3 (6 months) and T4 (12 months), the best-corrected visual acuity (BCVA), visual function index (VF value) and macular pigment density values (MPOD) were collected. Results The BCVA, VF value and MPOD In group A at T1-T4 were respectively higher than those in group B [BCVA (T1: 0.93±0.21 vs 0.84±0.19; T2: 0.93±0.20 vs 0.83±0.20; T3: 0.92±0.17 vs 0.80±0.18; T4: 0.87±0.21 vs 0.76±0.22)(P < 0.05, respectively). VF value (T1: 88.0±3.19 vs 85.9±14.09; T2: 86.1±2.55 vs 82.9±4.24; T3: 83.1±3.11 vs 79.2±4.93; T4: 79.9±4.37 vs 75.3±15.73) (P < 0.05, respectiely). MPOD (T1: 0.578±0.086 vsO.535±0.097; T2: 0.591±0.089 vs 0.520±0.088; T3: 0.585±0.091 vs 0.508±0.084; T4: 0.574±0.074 vs 0.486±0.070)(P < 0.05, respectively)]. No significant difference was deceted between the two groups in early postoperative omplications.Conclusion Prophylactic usage with lutein after cataract surgery may improve the macular and visual function of elderly.关键词
叶黄素/老年性白内障/黄斑/视功能Key words
lutein/senile cataracts/macula lutea/visual function分类
医药卫生引用本文复制引用
冷非,白大勇,梁天蔚,胡守龙,赵军阳,刘平,李莉..叶黄素对白内障术后患者黄斑及视觉功能的影响[J].解放军医学院学报,2017,38(5):414-416,448,4.基金项目
北京市属医院科研培育计划项目(BCHYIPA-2016-03) Supported by the Municipal Hospital Research and Development Program of Beijing (BCHYIPA-2016-03) （BCHYIPA-2016-03）
