解放军医学院学报2017，Vol.38Issue(5)：417-419,3.DOI:10.3969/j.issn.2095-5227.2017.05.008
新疆乌鲁木齐地区汉族健康体检者血清高密度脂蛋白胆固醇的流行病学调查
Prevalence of serum high density lipoprotein cholesterol in healthy Han Chinese subjects in Urumqi Xinjiang Uygur Autonomous Region
摘要
Abstract
Objective To investigate the prevalence of high density lipoprotein (HDL) in healthy Han Chinese subjects in Urumqi.Methods Health screening data of 35017 cases were retrospectively collected, and people with liver dysfunction, abnormal blood glucose, renal dysfunction were excluded. A total of 22643 cases(10265 males, 12378 females) were enrolled in and divided into 6 groups according to age. Serum high density lipoprotein cholesterol (high density lipoprotein, HDL-C) was detected using homogeneous method. Results Overall serum HDL-C was (1.42±0.33) mmol/L in our investigation, higher than national average of 1.30 mmol/L. Female had higher serum HDL-C level than male (1.51 mmol/L vs 1.24 mmol/L, P < 0.001). In male, serum HDL-C was higher in those aged over 60 years (60 - 69 group: 1.28(1.10, 1.47); ≥ 70 group:1.30(1.11, 1.51) ) than those in other age groups (30 - 39 group: 1.22 (1.07, 1.39) ; 40 - 49 group:1.22 (1.06, 1.41); 50 - 59 group: 1.23 (1.07, 1.41)) (P < 0.01, respectively). Inopposite, youngest female group aged 18 - 29 had highest level of HDL-C [1.54 (1.36, 1.75)] as compared with other age groups (P < 0.01, respectively). According to the guideline of prevention and treatment of dyslipidemia in China in 2007, 10.71% (2425/22643) of healthy subjects had low HDL-C ( < 1.04 mmol/L), and the incidence was higher in male (18.80%, 1930/10265) than in female (4.00%, 495/12378). This trend was also testified in the comparison between male and female in each age group.Conclusion The serum level of HDL-C of Chinese Han subjects in our study in Urumqi city is higher than the average level of Chinese adults. The percentage of low HDL-C was higher in male, and youngest female group has in highest HDL-C level.关键词
高密度脂蛋白/健康体检/流行病学分析Key words
high density lipoprotein/health examination/epidemiological analysis分类
医药卫生引用本文复制引用
王迎洪,王瑜,王淑霞,杨晓萍,吴建荣,王燕,马依彤..新疆乌鲁木齐地区汉族健康体检者血清高密度脂蛋白胆固醇的流行病学调查[J].解放军医学院学报,2017,38(5):417-419,3.基金项目
国家自然科学基金联合基金重点支持项目(U1403221) （U1403221）
新疆维吾尔自治区重点实验室专项基金项目(2014KL011) （2014KL011）
新疆维吾尔自治区自然科学基金医学联合基金(2015211C071) （2015211C071）
新疆医科大学研究生创新基金(CXCY001) Supported by the National Natural Science Foundation of China - Joint Fund Project (U1403221) （CXCY001）
Xinjiang Uygur Autonomous Region Key Laboratory of Special Fund Projects (2014KL011) （2014KL011）
Xinjiang Uygur Autonomous Region Natural Science Foundation-Medical Joint Fund (2015211C071) （2015211C071）
