摘要
Abstract
Objective To investigate the clinical effect of hepatectomy versus extracapsular peeling in the treatment of hepatic hemangioma,and to provide a basis for selection of surgical procedure in clinical practice.Methods A retrospective analysis was performed for the clinical data of 115 patients who underwent surgical treatment in The Affiliated Hospital of Xuzhou Medical University from January 2010 to May 2016.According to the surgical procedure,these patients were divided into peeling group (79 patients) and hepatectomy group (36 patients).According to the tumor diameter,the patients were further divided into two subgroups for stratified comparison:89 patients with hepatic hemangioma who had a tumor diameter of 5-10 cm were divided into large peeling group with 64 patients and large hepatectomy group with 25 patients;26 patients with a tumor diameter of ＞ 10 cm were divided into giant hemangioma peeling group with 15 patients and giant hemangioma hepatectomy group with 11 patients.The preoperative,intraoperative,and postoperative clinical data were compared between groups.The two-independent-samples t test was used for comparison of normally distributed continuous data,and the Mann-Whitney U test was used for comparison of non-normally distributed data between groups.The chi-square test and Fisher's exact test were used for comparison of categorical data between groups.Results There were no significant differences between the hepatectomy group and the peeling group in intraoperative blood loss [300 (200-400) ml vs 300 (225-500) ml,Z =-1.065,P =0.287],time of operation [120 (105-160) min vs 140 (95-150) min,Z =-0.036,P =0.971],postoperative drainage volume [280 (165-520) ml vs 310 (105-546) ml,Z=0.413,P=0.679],length of hospital stay [16 (14-19) d vs 14 (13-19.5) d,Z=-1.283,P=0.200],and hospital costs (27 973.64 ± 10 028.32 RMB vs 28 680.85-± 10 662.87 RMB,Z =-0.344,P =0.732).The subgroup analysis showed that there were also no significant differences between the hepatectomy group and the peeling group in intraoperative blood loss,time of operation,postoperative drainage volume,length of hospital stay,and hospital costs (all P ＞ 0.05).Conclusion Hepatectomy and hemangioma peeling have similar clinical effects in the treatment of hepatic hemangioma.关键词
肝肿瘤/血管瘤/肝切除术/剥脱术Key words
liver neoplasms/hemangioma/hepatectomy/enucleation分类
医药卫生
