临床肝胆病杂志2017,Vol.33Issue(5):829-832,4.DOI:10.3969/j.issn.1001-5256.2017.05.007
中草药相关药物性肝损伤的流行特点、主要原因与诊断评估
Epidemic features, major causes, and diagnostic evaluation of herb-induced liver injury
刘成海 1朱春雾1
作者信息
- 1. 上海中医药大学附属曙光医院肝病研究所,上海201203
- 折叠
摘要
Abstract
With the wide application of Chinese herbal medicine around the world and the continuous perfection of adverse drug reaction monitoring system,herb-induced liver injury (HILI) has attracted more and more attention,but its actual incidence remains unknown.As is reported in the literature,its constituent ratio ranged from 20% to 30% and there are many clinical types,among which hepatocellular injury is the most common type.There are many causes of HILI,including pharmaceutical factors,factors associated with the human body,lack of preclinical evaluation,and unreasonable clinical application.Currently it is difficult to make a diagnosis of HILI,and tracing the source of Chinese herbal medicine may play an important role in the diagnosis of this disease.Liver injury induced by Chinese herbal medicine should be taken seriously and active diagnosis and effective prevention and treatment should be performed.关键词
中草药/肝炎,中毒性Key words
drugs, Chinese herbal/hepatitis, toxic分类
医药卫生引用本文复制引用
刘成海,朱春雾..中草药相关药物性肝损伤的流行特点、主要原因与诊断评估[J].临床肝胆病杂志,2017,33(5):829-832,4.