药学研究2017，Vol.36Issue(5)：292-294,304,4.DOI:10.13506/j.cnki.jpr.2017.05.012
NLRP3和TLR4调控的细胞焦亡在痛风性关节炎中的作用
The effect of pyroptotic in gouty arthritis regulated by NLRP3 and TLR4
卢国 1郑东森 1李瀚文 1洪浩1
作者信息
- 1. 中国药科大学药理教研室,江苏 南京 210009
- 折叠
摘要
Abstract
Pyroptotic is a strongly pro-inflammatory process of programmed cell death mediated by caspase-1.Pyroptotic,regulated by NLRP3 inflammasome and TLR4 signaling pathways together,plays an important role in the process of gout arthritis disease.This paper systematically reviewed about pyroptotic mechanism system in gouty arthritis,provided direction for the research on new drugs.关键词
细胞焦亡/痛风性关节炎/NOD样受体蛋白3/半胱氨酸蛋白酶-1/Toll样受体蛋白4Key words
Pyroptotic/Gouty arthritis/NLRP3/Caspase-1/TLR4分类
医药卫生引用本文复制引用
卢国,郑东森,李瀚文,洪浩..NLRP3和TLR4调控的细胞焦亡在痛风性关节炎中的作用[J].药学研究,2017,36(5):292-294,304,4.
