山东医药2017，Vol.57Issue(17)：25-27,30,4.DOI:10.3969/j.issn.1002-266X.2017.17.008
急性心肌梗死合并多支血管病变患者早期完全血运重建的临床疗效及预后分析
Clinical efficacy and prognosis of complete revascularization for patients with acute myocardial infarction complicated with multivessel disease
摘要
Abstract
Objective To investigate the clinical efficacy and prognosis of different revascularization(complete or incomplete)for patients with acute myocardial infarction(AMI)complicated with multiple vessel disease(MVD)after emergency percutaneous coronary intervention(PCI).Methods The clinical data from 200 cases of AMI patients with MVD were retrospectively analyzed.According to the revascularization,we divided them into the complete revascularization group(82 cases,CR group)and the incomplete revascularization group(118 cases,IR group).After that,the CR group were divided into the early complete revascularization group(31 cases,CR1 group)and the elective complete revascularization group(51 cases,CR2 group).The baseline clinical characteristics,PCI treatment,drug use,clinical efficacy and long-term prognosis of the two groups were recorded.Results There was no significantly difference in the baseline clinical characteristics,general drug use,and coronary artery disease situation between the two groups(all P>0.05).CR group had a significantly higher number of stents than ICR group,and had less use of nitrates than IR group(all P<0.05).The recurrent angina,revascularization rate and major adverse cardiovascular events(MACE)of the IR group during hospitalization and post-hospital were significantly higher than those in the CR group within the 18-month follow-up.The recurrent angina pectoris and the incidence of MACE of the CR2 group was significantly higher than that in the CR1 group(all P<0.05).Cox proportional hazards regression analysis found that incomplete revascularization was an independent predictor for MACE(P<0.05).Conclusions The clinical curative effect and prognosis in patients with AMI and MVD receiving complete revascularization is superior to that of patients receiving incomplete revascularization by PCI,and the early complete revascularization is better than the selective complete revascularization.MACE is more likely to occur in patients treated with incomplete revascularization by PCI.关键词
心肌梗死,急性/冠脉多支病变/血运重建/经皮冠状动脉介入Key words
myocardial infarction/acute/multivessel coronary artery disease/revascularization/percutaneous coronary intervention分类
医药卫生引用本文复制引用
刘海龙,杨蕾,朱银川,杨雁华,汤建民..急性心肌梗死合并多支血管病变患者早期完全血运重建的临床疗效及预后分析[J].山东医药,2017,57(17):25-27,30,4.基金项目
河南省教育厅2015年度河南省高等学校重点科研项目(15A320028). （15A320028）
