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维生素D水平对产后小鼠情绪及运动能力的影响

段冬霞 刘小青 高正良

同济大学学报(医学版)2017,Vol.38Issue(2):28-32,44,6.
同济大学学报(医学版)2017,Vol.38Issue(2):28-32,44,6.DOI:10.16118/j.1008-0392.2017.02.006

维生素D水平对产后小鼠情绪及运动能力的影响

Effect of vitamin D on athletic performance and mood of postpartum mice

段冬霞 1刘小青 2高正良1

作者信息

  • 1. 同济大学附属第十人民医院转化医学中心,上海200072
  • 2. 同济大学医学院,上海200092
  • 折叠

摘要

Abstract

Objective To investigate the effects of vitamin D on postpartum mood and athletic performance in mice.Methods Vitamin D was given to postpartum mice for 14 weeks,with a normal dose (n =27,1 000 IU/kg),deficient dose (n =25,0 IU/kg) or overdose (n =22,10 000 IU/kg).The maternal depressive-like behaviors was examined by using tail suspension test (TST),forced swim test (FST),dark-light box (DLB),open field and rotarod for 10 weeks.Results Vitamin D had little effect on the athletic activity with open field and rotarod tests.Dark-light box revealed that there was no effect of vitamin D on the anxiety.In addition,tail suspension and forced swim tests indicated that vitamin D had no effect on postpartum depression.Conclusion Vitamin D shows no persistent effect on athletic activity and postpartum mood in mice.

关键词

维生素D/产后情绪/运动能力/行为测试/小鼠

Key words

vitamin D/postpartum mood/athletic performance/animal behavior test/mice

分类

生物科学

引用本文复制引用

段冬霞,刘小青,高正良..维生素D水平对产后小鼠情绪及运动能力的影响[J].同济大学学报(医学版),2017,38(2):28-32,44,6.

基金项目

国家自然科学基金(31371497) (31371497)

国家自然科学基金青年项目(31301063) (31301063)

同济大学学报(医学版)

OACSTPCD

1008-0392

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