中国水产科学2017，Vol.24Issue(3)：623-632,10.DOI:10.3724/SP.J.1118.2017.16331
麻痹性贝类毒素在栉孔扇贝体内的代谢轮廓
Metabolic profile of paralytic shellfish toxin in scallop Chlamys farreri
摘要
Abstract
Paralytic shellfish toxins (PSTs) are potent neurotoxins produced by a variety of marine dinoflagellates, such asGymnodinium,Alexandrium andPyrodinium. PSTs can accumulate and be passed into the food chain through the filter feeding of toxin-producing algae by bivalve mollusks. The consumption of contaminated shell-fish can cause poisoning in humans, with symptoms including nausea, vomiting, diarrhea, numbness or tingling in the extremities, and even death as a result of respiratory failure.A. tamarense is widely distributed along the coast of China, and often forms large algal blooms in the waters surrounding Nanhuangcheng Island, the Zhoushan area, and the port city of Xiamen. Many controlledin vivo feeding experiments with shellfish have investigated the ac-cumulation and fate of PSTs toxins in the marine food web. Comparative studies of PST profiles often found sig-nificant differences between the causative dinoflagellates and contaminated bivalve mollusks, thus indicating ac-tive metabolism of the toxin in some shellfish. The scallopsPatinopecten yessoensis andChlamys nipponensis are known to become much more toxic for consumption than mussels grown under the same environmental conditions, and several months are required until the toxicity drops to an acceptably safe level. Conversely, levels of toxicity in the short-necked clam and oysters are generally low, and the toxicity can decline as quickly as in the mussel. The metabolic interconversion of incorporated toxins achieved by enzymatic and chemical reactions in the tissues of bivalves, and different uptake and depuration kinetics of the individual toxins, may each contribute to differ-ences in the PST profiles.关键词
麻痹性贝类毒素/栉孔扇贝/塔玛亚历山大藻/蓄积/代谢/靶器官Key words
paralytic shellfish toxin/Chlamys farreri/Alexandrium tamarense/bioaccumulation/metabolism/target organs分类
资源环境引用本文复制引用
邴晓菲,吴海燕,王群,李清云,郭萌萌,国佼,翟毓秀,谭志军..麻痹性贝类毒素在栉孔扇贝体内的代谢轮廓[J].中国水产科学,2017,24(3):623-632,10.基金项目
山东省重点研发计划项目(2016GSF120018) （2016GSF120018）
中央级公益性科研院所基本科研业务费资助项目(2016HY-ZD1101, 20603022015017-1). （2016HY-ZD1101, 20603022015017-1）
