中国实用妇科与产科杂志2017，Vol.33Issue(5)：469-472,4.DOI:10.19538/j.fk2017050109
子宫内膜癌的化疗与内分泌治疗
Chemotherapy and hormonal therapy for endometrial cancers
摘要
Abstract
The objective of this essay is to conduct a critical appraisal of the published literature and clinical practices on the use of adjuvant chemotherapy and neo-adjuvant chemotherapy in the treatment of endometrial cancers.Chemotherapy is often recommended for high-risk subsets of stage Ⅰ disease.Level Ⅰ evidence exists for use of adjuvant chemotherapy in stage Ⅲ c endometrial cancer,although results of randomized trials have trials.Carboplatin plus paclitaxel is the current standard regimen,based on extrapolation of data from the metastatic setting.Neoadjuvant chemotherapy is performed followed by interval debulking for patients with poor performance status or those patients who the surgeon believes will have suboptimal debulking if surgery is attempted.Although hormonal therapy is not recommended in the adjuvant setting,it remains useful in the treatment of metastatic disease,particularly for tumors of low-grade endometrioid histology with a long time to recur.关键词
子宫内膜肿瘤/化疗/新辅助化疗/激素治疗Key words
endometrial neoplasm/chemotherapy/neo-adjuvant/hormonal therapy分类
医药卫生引用本文复制引用
高雨农..子宫内膜癌的化疗与内分泌治疗[J].中国实用妇科与产科杂志,2017,33(5):469-472,4.
