胆木叶药材的质量标准研究OA北大核心CSTPCD
Study on Quality Standard for the Leaves of Nauclea officinalis
目的:建立胆木叶药材的质量标准.方法:采用显微鉴别法和薄层色谱法(TLC)对药材进行定性鉴别;测定药材水分、灰分;采用高效液相色谱法测定药材中异长春花苷内酰胺含量:色谱柱为Lichrospher C18,流动相为乙腈-0.1%磷酸溶液(梯度洗脱),流速为1 mL/min,检测波长为226 nm,柱温为30℃,进样量为10μL.结果:胆木叶的显微鉴别特征性强,TLC图斑点清晰,分离度好,阴性对照无干扰.异长春花苷内酰胺检测质量浓度线性范围为0.01…查看全部>>
OBJECTIVE:To establish the quality standard for the leaves of Nauclea officinalis. METHODS:Microscopic identi-fication and TLC methods were used for qualitative identification of N. officinalis. The moisture and ash of medicinal materials were determined. HPLC method was adopted to determine the content of strictosamide in medicinal materials. The determination was per-formed on Lichrospher C18 column with mobile phase consisted of acetonitrile-0.1% phosphor…查看全部>>
张小强;吴云;杨一帆;王振中;丁岗
江苏康缘药业股份有限公司,江苏连云港 222001中药制药过程新技术国家重点实验室,江苏 连云港 222001江苏康缘药业股份有限公司,江苏连云港 222001中药制药过程新技术国家重点实验室,江苏 连云港 222001江苏康缘药业股份有限公司,江苏连云港 222001
医药卫生
胆木叶质量标准显微鉴别法薄层色谱法含量测定高效液相色谱法
Leaves of Nauclea officinalisQuality standardMicroscopic identificationTLCContent determinationHPLC
《中国药房》 2017 (15)
2097-2100,4
"重大新药创制"科技重大专项(No.2013ZX09402203)
评论