中国医院用药评价与分析2017，Vol.17Issue(5)：651-652,655,3.DOI:10.14009/j.issn.1672-2124.2017.05.028
胃复春片联合聚普瑞锌颗粒治疗萎缩性胃炎的疗效及对患者细胞炎症因子水平的影响
Efficacy of Weifuchun Tablets Combined with Polaprezine Granules in Treatment of Atrophic Gastritis and Effects on Inflammatory Cytokine Level
何东凌 1林丽梅 1林春霞1
作者信息
- 1. 河源市人民医院/暨南大学附属河源医院消化内科,广东 河源 517000
- 折叠
摘要
Abstract
Objective:To probe into the clinical efficacy of Weifuchun Tablets combined with Polaprezine Granules in treatment of atrophic gastritis and effects on inflammatory cytokine level.METHODS: 80 patients with atrophic gastritis admitted into Heyuan People`s Hospital/Heyuan Hospital Affiliated to Jinan University from Jun.2015 to Jun.2016 were selected to be divided into observation group and control group via the random number table,with 40 cases in each.The control group was treated with Polaprezine Granules,while the observation group additionally received Weifuchun Tablets based on the control group.The clinical efficacy of two groups were observed,differences of gastroscope score,chronic inflammation pathological histology score,serum cell inflammatory factor level and incidence of adverse drug reactions between two groups were compared before and after treatment.RESULTS: The total effective rate of observation group was 92.50％(37/40),significantly higher than that of control group [67.50％(27/40)],with statistically significant difference(P<0.05).After treatment,the gastroscope score,chronic inflammation pathological histology score,TNF-α and IL-6 levels in observation group were significantly lower than those in control group,with statistically significant difference(P<0.05).There was no severe adverse drug reactions in both groups.CONCLUSIONS: The clinical efficacy of Weifuchun Tablets combined with Polaprezine Granules in treatment of atrophic gastritis is remarkable,which can reduce the serum TNF-and IL-6 levels with high safety.关键词
聚普瑞锌/胃复春片/萎缩性胃炎Key words
Polaprezinc/Weifuchun tablets/Atrophic gastritis分类
医药卫生引用本文复制引用
何东凌,林丽梅,林春霞..胃复春片联合聚普瑞锌颗粒治疗萎缩性胃炎的疗效及对患者细胞炎症因子水平的影响[J].中国医院用药评价与分析,2017,17(5):651-652,655,3.
