中山大学学报（医学科学版）2017，Vol.38Issue(3)：438-442,5.
右美托咪定与舒芬太尼鼻内给药用于儿童口腔科门诊手术镇静的临床观察
Clinical Observation of Intranasal Dexmedetomidine and Sufentanil for Pediatric Sedation Undergoing Stomatology Operation of Outpatient Department
摘要
Abstract
[Objective] To research the sedative effect of intranasal dexmedetomidine and sufentanil for pediatric sedation for stomatological operation of outpatient department.[Methods] 60 children undergoing stomatological operation of outpatient department,age 3 ～ 7 years,weighing 10 ～ 32 kg,of ASA physical status Ⅰ ～ Ⅱ,were divided into the three groups (n =20) randomly using a random number table:group dexmedetomidine and sufentanil (group DS),group dexmetomidine (group D),group sufentanil (group S).Recorded the children's behavior using the Ohio State University behavior rating score (OSUBRS),the University of Michigan Sedation Score (UMSS),SBP,HR and side-effects when entry,during and leave operation and in post-anesthesia care unit,side-effects,the satisfaction of stomatological doctors and parents.[Results] The OSUBRS of group DS when entry,during operation were lower than group D (P ＜ 0.01).The UMSS of group DS were higher than group D and group S when entry and during operation (P ＜ 0.05).The success rate of group DS was higher than group D and group S (P ＜ 0.01).There was no different of mean percentage change in systolic blood pressure and heart rate from baseline between group DS and group D (P ＞ 0.05).There were no instances of respiratory depression,hypotension and bradycadia.[Conclusion] Intranasal dexmedetomidine and sufentanil provides satisfactory pediatric sedation for stomatological operation of outpatient department without side effects such as respiratory depression,bradycadia and hypotension.关键词
右美托咪定/舒芬太尼/鼻内投药/口腔科手术/清醒镇静Key words
dexmedetomidine/sufentanil/intranasal administration/stomatology operation/conscious sedation分类
医药卫生引用本文复制引用
储靖,李宏,蔡春妹,薛佩彤,霍金荣..右美托咪定与舒芬太尼鼻内给药用于儿童口腔科门诊手术镇静的临床观察[J].中山大学学报（医学科学版）,2017,38(3):438-442,5.基金项目
武警后勤学院附属医院面上项目(FYM201550) （FYM201550）
