中国中西医结合杂志2017，Vol.37Issue(5)：522-525,4.DOI:10.7661/j.cjim.20170315.032
经皮穴位电刺激联合腔内理疗治疗肾虚型卵巢低反应临床研究
Treatment of Poor Ovarian Response with Shen Deficiency by Transcutaneous Acupoint Electrical Stimulation Combined Intracavitary Physiotherapy
摘要
Abstract
Objective To observe the clinical effects of transcutaneous acupoint electrical stimulation combined intracavitary physiotherapy in treating poor ovarian response (POR) with Shen deficiency (SD) in in vitro fertilization-embryo transfer (IVF-ET).Methods Totally 92 POR patients undergoing IVF-ET were randomly assigned to the observation group and the control group,46 cases in each group.All patients received GnRH antagonist (GnRH-ant) protocol.Transcutaneous acupoint electrical stimulation combined intracavitary physiotherapy were administered to patients in the observation group during the menstrual cycle before superovulation cycle and during the superovulation process.Patients in the control group did not receive this treatment.The improvement of SD symptoms was observed before and after treatment in the two groups.Besides,the estradiol (E2) level on the day of human chorionic gonadotropin (HCG) injection,the amount and days of using gonadotropin (Gn),the number of retrieved oocytes,the fertilization rate,the available embryo rate,the high-quality embryo rate,and clinical pregnancy rate per embryo transfer cycle were observed.Results Compared with before treatment,scores of SD syndrome were significantly lower in the observation group (P ＜0.05).Compared with the control group after treatment,scores of SD syndrome significantly decreased (P ＜0.05),Gn dosage was significantly reduced (P ＜0.05),the level of E2 on the day of HCG significantly increased (P ＜0.01),the number of retrieved oocytes and fertilization rate significantly increased (P ＜0.05) in the observation group.Compared with control group,the number of days using Gn,the available embryo rate,the high quality embryo rate,and clinical pregnancy rate per embryo transfer cycle were not significantly different in the observation group (P ＞ 0.05).Conclusion Transcutaneous acupoint electrical stimulation combined intracavitary physiotherapy could increase the number of retrieved oocytes and the fertilization rate in patients with POR,reduce the Gn dosage,and improve symptoms of SD.关键词
经皮穴位电刺激/腔内理疗/卵巢低反应Key words
transcutaneous acupoint electrical stimulation/intracavitary physiotherapy/poor ovarian response引用本文复制引用
连方,李冉..经皮穴位电刺激联合腔内理疗治疗肾虚型卵巢低反应临床研究[J].中国中西医结合杂志,2017,37(5):522-525,4.基金项目
国家自然科学基金资助项目(No.81273790,No.81473720) （No.81273790,No.81473720）
