中国中西医结合杂志2017，Vol.37Issue(5)：526-529,4.DOI:10.7661/j.cjim.20170315.033
补肾调周法联合微刺激干预卵巢低反应不孕患者的临床研究
Treating Infertile Patients with Poor Ovarian Response by Cycle Regulating by Shen Supplementing Combined Microstimulation
摘要
Abstract
Objective To observe the effect of cycle regulating by Shen supplementing combined microstimulation on infertile patients with poor ovarian response (POR),and to study its feasibility and validity for POR patients in controllable ovarian stimulation cycle.Methods Totally 76 POR patients were randomly divided into the treatment group and the control group,38 in each group.Patients in the control group received microstimulation program,while those in the treatment group additionally took Chinese herbal decoction for Shen supplementing and cycle regulating.The course of treatment was 3 months.Improved conditions of Shen yin deficiency syndrome,days for Gn use,Gn dosage,E2 level on HCG injection day,oocyte retrieval numbers,M Ⅱ oocyte numbers,M Ⅱ oocyte fertilization rate,high quality embryo number and high quality embryo rate,cycle cancellation rate,endometrial thickness on embryo transfer (ET) day,biochemical pregnancy rate,and clinical pregnancy rate were compared.Results The total effective rate of the treatment group was 94.7％ (36/38),significantly higher than that of the control group [76.3％ (29/38),P ＜ 0.05].The obtained oocyte numbers,M Ⅱ oocyte numbers,high quality embryo number and high quality embryo rate,endometrial thickness on ET day were significantly higher in the treatment group than in the control group (P ＜0.05,P ＜0.01).There were no statistical differences in days for Gn use,Gn dosage,E2 level on HCG day,M Ⅱ occyte fertilization rate,cycle cancellation rate,biochemical pregnancy rate,or clinical pregnancy rate between the two groups (P ＞0.05).Conclusion Cycle regulating by Shen supplementing method could increase oocyte retrieval numbers and M Ⅱ oocycet numbers in ovarian stimulation cycle,elevate high quality embryo rate,endometrial thickness and pregnancy rate.关键词
补肾调周法/微刺激/卵巢低反应Key words
cycle regulating method by Shen supplementing/microstimulation/poor ovarian response引用本文复制引用
左文婷,谈勇,殷燕云,杨琳..补肾调周法联合微刺激干预卵巢低反应不孕患者的临床研究[J].中国中西医结合杂志,2017,37(5):526-529,4.基金项目
江苏省中医药局资助项目(No.BL2013039) （No.BL2013039）
