中国中西医结合杂志2017，Vol.37Issue(5)：530-533,4.DOI:10.7661/j.cjim.20170315.034
补肾调肝方对非肥胖型多囊卵巢综合征患者糖脂代谢的影响
Effects of Bushen Tiaogan Recipe on Glucolipid Metabolism in Non-obese Patients with Polycystic Ovary Syndrome
摘要
Abstract
Objective To observe the effects of Bushen Tiaogan Recipe (BTR) on glucolipid metabolism in patients with polycystic ovary syndrome (PCOS).Methods Totally 60 non-obese PCOS patients [body mass index (BMI) ＜25] with Shen deficiency Gan-qi stagnation syndrome were randomly assigned to the treatment group and the control group,30 in each group.Patients in the treatment group took BTR (Yulinzhu Decoction and Chaihu Shugan Powder),one dose per day,taken once in the morning and once in the evening.Patients in the control group took Metformin Tablet (MT),1 000 mg each time,twice per day,taken with meals once in the morning and once in the evening.The treatment course was 3 months for all.Fasting plasma glucose (FPG),fasting insulin (FINS),homeostasis model assessment-insulin resistance (HOMA-IR),TC,TG,body mass index (BMI),waist hip ratio (WHR),luteinizing hormone (LH),follicle stimulating hormone (FSH),LH/FSH,and free testosterone (T) were measured before and after treatment.Results Compared with before treatment in the same group,FPG,FINS,LH/FSH,and BMI decreased in the control group (P ＜0.05,P ＜0.01);FPG,TC,LH,LH/FSH,WHR,and BMI decreased in the treatment group (P ＜0.05,P ＜0.01).Statistical significance existed in WHR,BMI,FINS,and LH between the control group and the treatment group (P ＜0.05).Conclusions Non-obese PCOS patients weren't characterized by insulin resistance.BTR could improve glucolipid metabolism of non-obese PCOS patients by decreasing LH level and LH/FSH.In this way it played therapeutic roles for non-obese PCOS patients.关键词
补肾调肝方/非肥胖型多囊卵巢综合征/肾虚肝郁/体重指数/总胆固醇/糖脂代谢Key words
Bushen Tiaogan Recipe/non-obese polycystic ovary syndrome/Shen deficiency Ganqi stagnation/body mass index/total cholesterol/glucolipid metabolism引用本文复制引用
孙忻,丁彩飞,杨欣,展晓日..补肾调肝方对非肥胖型多囊卵巢综合征患者糖脂代谢的影响[J].中国中西医结合杂志,2017,37(5):530-533,4.基金项目
国家名老中医工作室科研项目 （）
浙江省中医药管理局青年基金资助项目(No.2010ZQ012) （No.2010ZQ012）
杭州市科学技术委员会重点专病专科项目(No.20150733Q38) （No.20150733Q38）
杭州市科技局课题资助项目(No.20100733Q24) （No.20100733Q24）
