摘要
Abstract
Objective To observe the effect of Yiqi Yangyin Huoxue Recipe (YYHR) on early diabetic cardiomyopathy patients.Methods Totally 80 early diabetic cardiomyopathy patients were randomly assigned to the control group and the treatment group,40 cases in each group.All patients received basic treatment of hypoglycemics.Those in the control group additionally took Atorvastatin Calcium Tablet (ACT),while those in the treatment group additionally took YYHR.The therapeutic course for all was 12 weeks.Changes of fasting blood glucose (FBG),glycosylated hemoglobin A1c(HbA1c),TC,TG,LDL-C,HDL-C,2 h postprandial blood glucose (2 h PG),left ventricular ejection fraction (LVEF),E/A ratio,and efficacy of TCM syndromes were observed in the two groups before and after treatment.Results Compared with before treatment in the same group,levels of FBG,2 h PG,HbA1c,TC,TG,and LDL-C all decreased in the two groups after treatment (P ＜0.05);HDL-C increased in the treatment group after treatment (P ＜0.05);LVEF and E/A ratio were improved in the two groups after treatment (P ＜0.05).Compared with the control group,FBG,2 h PG,HbA1c,TC,TG,and LDL-C all obviously decreased,HDL-C was elevated,LVEF and E/A ratio were obviously improved in the treatment group after treatment (all P ＜0.05).The efficacy of TCM syndromes was 90.0％ (36/40) in the treatment group,obviously better than that of the control group [67.5％ (27/40)] with statistical difference (X2 =4.781,P =0.028).Conclusion YYHR could auxiliarily lower blood glucose,regulate blood lipids,improve ventricular diastolic function,and improve the efficacy of TCM syndromes in treatment of early diabetic cardiomyopathy.关键词
糖尿病心肌病/早期/益气养阴活血方Key words
diabetic cardiomyopathy/early stage/Yiqi Yangyin Huoxue Recipe
