中国中西医结合杂志2017，Vol.37Issue(5)：612-616,5.DOI:10.7661/j.cjim.20170330.059
冠心病痰瘀互结证病机转化为阻络、化火、生毒证候宏观及微观诊断指标的权重研究
Macroscopic and Microscopic Diagnostic Indicators of Weight Research on Coronary Heart Disease with Intermingled Phlegm and Blood Stasis Syndrome Transforming Collaterals Blocking,Fire Generating, Toxic Producing Syndromes
摘要
Abstract
Objective To study indicated diagnostic weight of the syndrome diagnosis indices of coronary heart disease (CHD) patients with phlegm and blood stasis syndrome (PBSS),thus providing diagnostic criteria for it.Methods Experts of TCM cardio-/cerebral vascular diseases with rich clinical experiences were invited across China to fill in questionnaire on the degrees of diagnostic criteria for the 3 syndromes (collaterals blocking syndrome,fire generating syndrome,toxic producing syndrome).The weight of all the diagnostic items was defined by using principal component analysis (PCA) and the comprehensive evaluation function.Results (1) The order of indicated diagnostic weight for collaterals blocking syndrome:palpitation,unsmooth pulse,recurrent chest pain and difficulties for healing,plaque vulnerability,enhanced inflammatory activity,numbness of limbs,irritability,chest tightness,string pulse,plaque formation.(2) The order of indicated diagnostic weight for fire generating syndrome:plaque formation,plaque vulnerability,enhanced inflammatory activity,heartache like burning,irritability,rapid pulse,bitter taste,yellow tongue fur,red tongue,dry throat,dark urine,constipation.(3) The order of indicated diagnostic weight for toxic generating syndrome:sore throat,aphtha,severe bitter taste,dangerous situation,sublingual collaterals purplish red or reddish purple,old tongue,peeling off tongue coating,moderate and severe angina pectoris,unsmooth pulse,plaque formation,plaque vulnerability,blue or purple tongue,enhanced inflammatory activity,intermittent pulse.Conclusions The indicated diagnostic weight of CHD with PBSS were as follows.Collaterals blocking syndrome had important reference indicators on palpitation,unsmooth pulse,recurrent chest pain and difficulties for healing.Numb extremities and irritability were of important values.Fire generating syndrome had important reference indicators on heartache like burning,irritability,rapid pulse,bitter taste,yellow tongue fur,red tongue.Toxic generating syndrome had important reference indicators on sore throat,aphtha,severe bitter taste,dangerous situation,sublingual collaterals purplish red or reddish purple,old tongue.Plaque and inflammatory activity in the three syndromes had a larger weight,which had important reference indicators in clinical syndrome differentiation.关键词
主成分分析法/冠心病/痰瘀互结证/证候诊断指标Key words
principal component analysis/coronary heart disease/intermingled phlegm and blood stasis syndrome/indicators for syndrome diagnosis引用本文复制引用
段飞,胡镜清..冠心病痰瘀互结证病机转化为阻络、化火、生毒证候宏观及微观诊断指标的权重研究[J].中国中西医结合杂志,2017,37(5):612-616,5.基金项目
国家重点基础研究发展计划(No.2014CB542903) （No.2014CB542903）
中国中医科学院中医基础理论研究所第九批自主选题研究生资助项目(No.YZ-1545) （No.YZ-1545）
