摘要
Abstract
Objective:To compare the clinical characteristics of incomplete Kawasaki disease (IKD) and complete Kawasaki disease (CKD),to improve the awareness about IKD and decrease misdiagnosis rate of IKD.Methods:The clinical data of 105 children with Kawasaki disease in Shiyan Traditional Chinese Medicine Hospital from January 2004 to December 2013 were analyzed retrospectively,80 cases were CKD and 25 cases were IKD.The clinical characteristics,laboratory examination,organ damage,diagnosis time and hospitalization time between the two groups were compared and analyzed.Results:There were no significant differences in gender and age (P＞0.05),but there was significant difference in age ＜ 1 year between the two groups (x2 =5.47,P＜0.05).Compared with CKD group,the incidences of oral mucosal lesions,finger toe peeling,skin rash,perianal desquamation and lymph node enlargement in IKD group decreased (x2 =6.11,16.51,15.80,9.14,9.88,P＜0.05 or P＜0.01).The laboratory examinations including white blood cell (WBC),hematocrit (HCT),maximum platelet (PLT) count,C-reactive protein (CRP),erythrocyte sedimentation rate (ESR),albumin (ALB) had no statistical significance differences between two groups (P＞0.05).The incidences of coronary artery dilation (CAD),valvular regurgitation,ECG abnormal in IKD group were higher than those in CKD group (x2 =13.22,4.14,3.96,P＜0.05 or P＜0.01).The diagnostic time and hospitalization time in IKD group were (6.25±3.05) d and (13.85±5.10) d,which were higher than (4.50±2.25) d and (11.25±4.50) d in CKD group (t=3.11,2.44,P＜0.05 or P＜0.01).All KD children were cured or improved by immunoglobulin (IVIG) and aspirin treatment.Conclusion:The clinical manifestations of IKD are atypical,there is no significant difference comparing with CKD in laboratory examinations,and the incidence of coronary artery disease (CAL) is higher than that of CKD.Clinicians should give early diagnosis and treatment as soon as possible under laboratory and cardiac imaging examination.关键词
不完全川崎病/典型川崎病/临床特征/冠状动脉损害Key words
incomplete Kawasaki disease/complete Kawasaki disease/clinical characteristics/coronary artery lesion分类
医药卫生
