摘要
Abstract
Objective To analyze the clinical and pathological characteristics of patients with adenomyosis combined with endometrial carcinoma and compare the high risk factors and their significance for recurrence and prognosis between adenomyosis combined with endometrial carcinoma and pure endometrial carcinoma.Methods The clinical and pathological data of 307 endometrial carcinoma patients hospitalized in the Second People's Hospital of Liangshan City during February 2005 to July 2015 were analyzed retrospectively.Patients were divided into merge adenomyosis with endometrial carcinoma group (10.1％,group A) and pure endometrial carcinoma group (89.9％,group B).The clinical stage,pathological type,depth of myometrial invasion,estrogen receptor (ER) and progesterone receptor expression (PR),cytological typing,ascites cytology,lymph node metastasis,recurrence rate,survival rate without disease for 3 years,overall survival for 3 years between two groups were compared.Results Compared to group B,group A was more superficial in myometrial invasion,better in tissue differentiation,higher in PR tested positive rate,higher in ER tested positive rate lower recurrence rate,higher survival rate without disease for 3 years and higher overall survival rate.The differences were statistically significant (x2 value was 4.065,6.285,4.480,6.813,4.98,12.45 and 17.87,respectively,all P ＜ 0.05).There were no significant differences between two groups in the surgical pathological stage,age,menopause rate,body mass index,positive rate of ascites cytology,lymph node metastasis and pathological type (x2 value was 1.47,2.31,1.22,1.76,1.21,2.04 and 2.57,respectively,all P ＞0.05).Conclusion Adenomyosis combined with endometrial carcinoma mostly belongs to an estrogen-dependent tumor.It is of better differentiated tissue and superficial myometrial invasion.Compared to patients with pure endometrial carcinoma,the patients with adenomyosis combined with endometrial carcinoma are of less high risk factors.After surgery,patients with adenomyosis combined with endometrial carcinoma present low recurrence rate,high survival rate without disease for 3 years,high overall survival rate and good prognosis.关键词
子宫内膜癌/子宫腺肌病/子宫腺肌病合并子宫内膜癌/病理分析Key words
adenomyosis/endometrial carcinoma/adenomyosis coexisting with endometrial carcinoma/pathological analysis分类
医药卫生
