闫辉 1李正明 1张莲花 1杨永慧 1赵晖 1孙绪德1
作者信息
- 1. 第四军医大学第二附属医院麻醉科,西安710038
- 折叠
摘要
Abstract
Objective:To assess the efficacy of oxycodone with intercostal nerve blockade for postoperative analgesia in elderly after thoracotomy.Methods:One hundred and twenty patients,aged 65-75 years,both sexes,with BMI of 18-25 kg/m2,American Society of Anesthesiologists (ASA) Ⅰ-Ⅱ,scheduled for elective thoracotomy,were randomly divided into four groups using a random number:Group A (oxycodone),Group B (oxycodone with intercostal blockade),Group C (sufentanil),Group D (sufentanil with intercostal blockade).Patient controlled intravenous analgesia (PCIA) solution contained oxycodone 50 mg in 100 mL NS,without background infusion,Bolus 4 mL,lockout interval 5 min in group A and B.PCIA solution contained sufentanil 150 μg in 100 mL NS,basal infusion 2 mL/h,Bolus 0.5 mL,lockout interval 5 min in group C and D.Before closure of the chest,group B and D use intercostal nerve blockade.The visual analogue scale (VAS) of both rest and cough,analgesics dosage,level of patient's satisfaction with analgesia,and analgesia-related adverse events were recorded.Results:Group A showed comparable for pain relief both at rest and cough,adverse effects have no significantly differences than Group C;Group B use less analgesics than Group A,adverse events have no significantly differences,and lower incidence of nausea and vomiting than Group C and D.Conclusion:Oxycodone showed comparable for pain relief both at rest and cough than sufentanil in PCIA;oxycodone with intercostal nerve blockade reduced analgesics dosage and incidence of nausea and vomiting in elderly thoracotomy.关键词
羟考酮/肋间神经阻滞/舒芬太尼/镇痛/老年患者Key words
oxycodone/intercostal nerve blockade/sufentanil/pain/elderly
