临床与病理杂志2017，Vol.37Issue(4)：772-778,7.DOI:10.3978/j.issn.2095-6959.2017.04.021
基于meta分析的肿瘤患者经外周置入中心静脉导管相关性静脉血栓形成风险预测模型构建
Establishment of risk predictive model of venous thromboembolism associated with peripherally inserted central catheters among cancer patients based on meta-analysis
田旭 1陈慧 1宋国敏 2卞薇 3刘晓玲 4陈伟庆1
作者信息
- 1. 重庆市肿瘤研究所/肿瘤医院/癌症中心消化内科,重庆400030
- 2. 天津市天津医院护理部,天津300211
- 3. 第三军医大学西南医院眼科,重庆400038
- 4. 重庆市护理学会循证护理专业委员会,重庆400038
- 折叠
摘要
Abstract
Objective:Using meta-analysis technique to establish the risk predictive model of venous thromboembolism associated with peripherally inserted central catheters among cancer patients.Methods:The per-and prospective studies exploring risk factors contributing to development of venous thromboembolism associated with peripherally inserted central catheters among cancer patients were systematically identified.Meta-analysis technique was used to calculate the pooled odds ratio (ORP) after appraising the quality of eligible studies.And the risk predictive model will be established based on the values of translated the using natural logarithm approach.Results:Six studies were included.The sample size was 1 277 with 253 cases in the venous thromboembolism group and 1 024 cases in the control group.The incidence rate of venous thromboembolism associated with PICC was 19.81％.After screening,8 factors were included in the model,including COPD,hypertension,diabetes,history of chemotherapy and less activity,with pooled OR of 1.824,1.624,1.986,3.074 and 1.563,respectively.Conclusion:The present study establishes the risk predictive model of venous thromboembolism associated with peripherally inserted central catheters among cancer patients which was characterized by evidence-based basis using meta-analysis technique.关键词
肿瘤/导管相关性血栓/meta分析/logistic回归/风险预测模型Key words
neoplasm/catheter-related thrombosis/meta-analysis/logistic regression/risk predictive model引用本文复制引用
田旭,陈慧,宋国敏,卞薇,刘晓玲,陈伟庆..基于meta分析的肿瘤患者经外周置入中心静脉导管相关性静脉血栓形成风险预测模型构建[J].临床与病理杂志,2017,37(4):772-778,7.
