海南医学院学报2017，Vol.23Issue(8)：1056-1058,1062,4.DOI:10.13210/j.cnki.jhmu.20170406.048
血清PCT含量对重症急性胰腺炎患者炎症反应、RAS激活程度的评估价值
Value of serum PCT in the evaluation of inflammatory response and RAS activation in patients with severe acute pancreatitis
摘要
Abstract
Objective: To study the value of serum PClevelfoassessing the inflammatory response and RAactivation degree in patientwith severe acute pancreatitis.Methods: total of 76 patientwith acute pancreatitiwho were treated in ouhospital between May 2013 and April 2016 were collected, and 50 patientwith pure diarrhewho received infusion treatmenin ouhospital during the same period were selected athe control group.Serum PClevelof both groupwere detected, and the observation group were furthedivided into high PCgroup and low PCgroup (n=38) according to the median of PClevels.Enzyme-linked immune-sorbenassay (ELISA) waused to determine serum levelof pro-inflammatory factors, anti-inflammatory factorand RAindexes.Results: Serum PClevel of observation group wahighethan thaof control group (P<0.05);serum pro-inflammatory factorIL-1β, IL-6, CRP and TNF-α levelof high PCgroup and low PCgroup were highethan those of control group, anti-inflammatory factorIL-4, IL-10 and IL-13 levelwere highethan those of control group, and RAindexeAngⅡ, Rand ALD levelwere highethan those of control group (P<0.05);serum pro-inflammatory factorIL-1β, IL-6, CRP and TNF-α levelof high PCgroup were highethan those of low PCgroup, anti-inflammatory factorIL-4, IL-10 and IL-13 levelwere highethan those of low PCgroup, and the RAindexeAngⅡ, Rand ALD levelwere highethan those of low PCgroup (P<0.05).Conclusions: The serum PClevelcan assesthe inflammatory response and RAactivation degree in the patientwith severe acute pancreatitis.关键词
重症急性胰腺炎/降钙素原/炎症反应/肾素-血管紧张素-醛固酮Key words
Severe acute pancreatitis/Procalcitonin/Inflammatory response/Renin-angiotensin-aldosterone分类
医药卫生引用本文复制引用
武可,白晶利,王卫,陈莹,邱洁..血清PCT含量对重症急性胰腺炎患者炎症反应、RAS激活程度的评估价值[J].海南医学院学报,2017,23(8):1056-1058,1062,4.基金项目
邯郸市科技局科技研发计划项目(1623208066-2) （1623208066-2）
It was supported by Research and Development Projects of Handan Science and Technology Bureau of Science and Technology (No.1623208066-2). （No.1623208066-2）
