江苏大学学报（医学版）2017，Vol.27Issue(3)：257-260,4.DOI:10.13312/j.issn.1671-7783.y170082
不同b值磁共振弥散加权成像在甲状腺结节良恶性鉴别诊断中的价值
Utility of different b-values diffusion-weighted MR imaging indifferentiating malignant from benign thyroid nodules
陆瑜 1谌业荣 2胡曙东 2崔恒武 1李君荣1
作者信息
- 1. 江苏大学医学院, 江苏 镇江 212013
- 2. 江苏大学附属人民医院医学影像中心, 江苏 镇江 212002
- 折叠
摘要
Abstract
Objective:To assess the efficacy of using different b values diffusion weighted imaging(DWI) of MRI in the evaluation of thyroid nodule malignancy.Methods:Seventy-seven patients with single or multiple thyroid nodules(totally 120 nodules)were included in this study.The thyroid nodules` ADC (apparent diffusion coefficient) with different b values were assessed by Independent-Sample t test.Receiver operating characteristic (ROC) curves were drawn.Results:Malignant thyroid nodules showed significantly lower ADC than benign ones.The b-300 s/mm2 ADC values of benign and malignant thyroid nodules was(2.113±0.639)×10-3 and(1.784±0.544)×10-3mm2/s respectively;the b-500 s/mm2 ADC values was(1.856±0.547)×10-3 and(1.488±0.412)×10-3mm2/s respectively;the b-800 s/mm2 ADC values of benign and malignant nodules was(1.484±0.556)×10-3 and (1.264±0.356)×10-3mm2/s respectively.Sensitivity was 76.00%,84.00% and 73.97%,respectively;specificity was 51.11%, 46.67% and 60.00%,respectively;positive predictive value was 68.0%, 67.9% and 70.2%,respectively;negative predictive value was 63.5%, 70.2% and 63.8%, respectively.Conclusion:Different b values ADC may help differentiating benign thyroid nodules from malignant ones, but it is not sufficient to differentiate thyroid nodules` malignancy by using one of any b value ADC alone.关键词
甲状腺结节/甲状腺癌/磁共振成像/弥散加权成像Key words
thyroid nodule/thyroid carcinoma/magnetic resonance imaging/diffusion weighted imaging分类
医药卫生引用本文复制引用
陆瑜,谌业荣,胡曙东,崔恒武,李君荣..不同b值磁共振弥散加权成像在甲状腺结节良恶性鉴别诊断中的价值[J].江苏大学学报（医学版）,2017,27(3):257-260,4.
