江西农业学报2017,Vol.29Issue(5):77-81,5.DOI:10.19386/j.cnki.jxnyxb.2017.05.16
多浪羊多胎基因全基因组关联分析研究
Whole Genomic Association Analysis of Polyembryonic Gene in Duolang Sheep
王珊 1李晓林 2牛志刚 1史洪才2
作者信息
- 1. 石河子大学 动物科技学院,新疆 石河子 832003
- 2. 农业部草食家畜遗传育种与繁殖重点开放实验室/新疆维吾尔自治区畜牧科学院 生物技术研究中心,新疆 乌鲁木齐 830000
- 折叠
摘要
Abstract
The whole genomic association analysis (GWAS) of lambing traits of Duolang sheep was conducted by using the whole genomic resequencing technique, and the candidate genes and molecular markers related to the breeding traits of sheep were excavated.The Fst test screened out 135 significant windows, and their Fst value was mostly concentrated within 0.35~0.50.A total of 51 genes were obtained by the gene annotation to the selected significant windows.The further enrichment analysis found that the maximum value of Fst was 0.8710, and it was located within the gene NCOA1.In the female gametogenic clauses, the common gene of polyembryonic group and unigerminal group was INHBA.Through using ENSEMBLE database for gene annotation, a total of 28 genes (such as ACP1, ING5, ARNT, etc.) had intersection with the significant window.The disclosure of these candidate genes and molecular markers has reference value and theoretical significance for the excavation of functional genes related to sheep reproductive traits.关键词
全基因组关联分析/多浪羊/多胎Key words
Whole genomic association analysis/Duolang sheep/Polyembryony分类
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王珊,李晓林,牛志刚,史洪才..多浪羊多胎基因全基因组关联分析研究[J].江西农业学报,2017,29(5):77-81,5.