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牙髓干细胞在口腔颌面部骨组织工程中的应用进展

齐颖

口腔颌面外科杂志2016,Vol.26Issue(6):446-451,6.
口腔颌面外科杂志2016,Vol.26Issue(6):446-451,6.DOI:10.3969/j.issn.1005-4979.2016.06.015

牙髓干细胞在口腔颌面部骨组织工程中的应用进展

Recent Advances of Dental Pulp Stem Cells in Maxillofacial Region Tissue Engineering

齐颖1

作者信息

  • 1. 同济大学口腔医院·同济大学附属口腔医院儿童口腔科,上海牙组织修复与再生工程技术研究中心,上海 200072
  • 折叠

摘要

Abstract

Maxillofacial and periodontal bone defect can be caused by multiple diseases. Bone tissue engineering is an effective method to repair bone defects in maxillofacial and periodontal area. To achieve this, ideal seed cells are essential. Dental pulp stem cells (DPSCs) have been demonstrated to possess several appealing qualities: convenient access to the collection site, low morbidity, high efficiency during extraction and culture, osteogenic differentiation potential, and high interactivity with scaffold materials. Hence DPSCs become an ideal seed cell for tissue-engineered bone. In this review, we will look into the applications of DPSCs in maxillofacial and periodontal tissue-engineered bone.

关键词

牙髓干细胞/成骨分化/颌面部骨缺损/牙周骨缺损/组织工程骨

Key words

dental pulp stem cells (DPSCs)/osteogenic differentiation/maxillofacial bone defects/periodontal bone de-fects/tissue-engineered bone

分类

医药卫生

引用本文复制引用

齐颖..牙髓干细胞在口腔颌面部骨组织工程中的应用进展[J].口腔颌面外科杂志,2016,26(6):446-451,6.

基金项目

上海市科学技术委员会科研计划项目(14411963600) (14411963600)

口腔颌面外科杂志

OACSTPCD

1005-4979

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