内科理论与实践2017，Vol.12Issue(2)：103-106,4.DOI:10.16138/j.1673-6087.2017.02.007
脑梗死自发性出血性转化的影响因素分析
Analysis of factors influencing hemorrhagic transformation of cerebral infarction
摘要
Abstract
Objective To explore the influencing factors of hemorrhagic transformation of cerebral infarction.Methods A retrospective analysis of 149 patients with cerebral infarction was performed.Patients with hemorrhagic transformation were categorized as the observation group (n=68) and patients without hemorrhagic transformation were served as the control group (n=81).Compare the differences of the factors including sex,age,atrial fibrillation,hypertension,diabetes,previous stroke,blood glucose level,cholesterol level,number of blood platelet,blood coagulation function,use of anticoagulant and antiplatelet drugs,and size of infarct between the two groups.Single variant analysis and Logistic regression analysis were performed to identify the factors significantly associated with hemorrhagic transformation of cerebral infarction.Results Age,hypertension,activated partial thromboplastin time(APTT) and large size infarct were different significantly between the two groups (all P＜0.05),and Logistic regression analysis revealed that APTT and large size infarct were independent risk factors of hemorrhagic transformation.Conclusions Patients with long APTT and large size infarct may have higher risk of hemorrhagic transformation.关键词
脑梗死/出血性转化/影响因素Key words
Cerebral infarction/Hemorrhagic transformation/Influence factors分类
医药卫生引用本文复制引用
欧茹,李飞,邹腾甜,唐亚梅..脑梗死自发性出血性转化的影响因素分析[J].内科理论与实践,2017,12(2):103-106,4.基金项目
国家自然科学基金项目(项目编号:81471249、81622041) （项目编号:81471249、81622041）
广东省自然科学基金项目(项目编号:2014A030313120) （项目编号:2014A030313120）
佛山市卫生和计生局医学科研课题(项目编号:20160216) （项目编号:20160216）
