内科理论与实践2017,Vol.12Issue(2):107-110,4.DOI:10.16138/j.1673-6087.2017.02.008
慢性酒精中毒性脑病的临床观察
Clinical investigation of chronic alcohol encephalopathy
李红红 1张晓旎 1黎祥喷 1李艺 1何蕾 1彭英1
作者信息
- 1. 中山大学孙逸仙纪念医院神经科,广东广州510120
- 折叠
摘要
Abstract
Objective To study the clinical characteristics of chronic alcohol encephalopathy for providing a guidance for clinical diagnosis and treatment.Methods A retrospective study was performed to analyze the clinical manifestations,imaging characteristics and therapeutic effect in 75 cases of chronic alcohol encephalopathy.Results The patients were 73 male,2 female,and the onset of disease was between 29 and 73 years old [mean (49.69±12.54) years].The clinical manifestations showed great diversity:mental symptoms (40 cases,53.3%),limbs tremor (15 cases,20.0%),dizzy (15 cases,20.0%),nystagmus (13 cases,17.3%),memory impairment (13 cases,17.3%),ataxia (1 1 cases,14.7%),limbs anesthesia (9 cases,12.0%).CT/MRI finding included brain atrophy (44 cases),demyelinated changes (6 cases),and cerebral infarct (18 cases).Abstinence combined with vitamin B supplement and removal of oxygen free radical therapy could achieve a gratifying curative efficacy.Conclusions Chronic alcohol encephalopathy is prone to be misdiagnosed because of its diverse clinical characteristics.CT/MRI scan can provide scientific basis for clinical diagnosis and treatment.Vitamin B supplement combined with removal of oxygen free radical generally can afford a gratifying clinical improvement.关键词
酒精中毒/脑病/精神异常/脑萎缩/脱髓鞘Key words
Alcoholism/Encephalopathy/Mental abnormalities/Brain atrophy/Demyelination分类
医药卫生引用本文复制引用
李红红,张晓旎,黎祥喷,李艺,何蕾,彭英..慢性酒精中毒性脑病的临床观察[J].内科理论与实践,2017,12(2):107-110,4.