摘要
Abstract
Objective To investigate the possible influencing factors for cognitive function impairment in the elderly,so that early intervention of relevant factors could be fulfilled to delay the cognitive function impairment.Methods The Montreal cognitive assessment scale (MoCA) was used to assess the cognitive function in 202 patients,and the patients were divided into cognitive function impaired group and cognitive function normal group.To analyze the association between the possible influencing factors and cognitive function.Results The study included 202 patients,consisted of cognitive function impaired group 142 cases(70.3%) and cognitive function normal group 60 cases(29.7%).Age,educational level,blood pressure,diabetes mellitus,hyperlipidemia,atrial fibrillation,carotid artery atherosclerosis were different significantly between the two groups (all P<0.05).Multivariate Logistic regression analysis showed that among the above 7 factors,age [odds ratio (OR)=4.407,95% confidence interval (CI):2.084-9.320],hypertension (OR=7.597,95%CI:2.478-23.297),diabetes (OR=2.975,95%CI:1.191-7.428),hyperlipidemia (OR=8.977,95%CI:2.913-27.659),carotid atherosclerosis (OR=4.400,95%CI:1.636-11.836) and atrial fibrillation (OR=3.183,95%CI:1.059-9.566) were independent risk factors for cognitive function impairment,and culture level (OR=0.305,95%CI:0.153-0.607) was the protective factor for cognitive function.Conclusions The prevalence rate of cognitive function impairment in elderly is high.Age,hypertension,diabetes,hyperlipidemia,atherosclerosis,atrial fibrillation are risk factors of cognitive function impairment,and education is a protective factor for cognitive function.关键词
老年人/认知功能减退/危险因素Key words
Elderly/Cognitive impairment/Risk factor分类
医药卫生