上海针灸杂志2017，Vol.36Issue(6)：692-696,5.DOI:10.13460/j.issn.1005-0957.2017.06.0692
通元针法联合药物治疗顽固性多囊卵巢综合征不孕临床观察
Clinical Observation ofTongYuanNeedling Method plus Letrozol and HCG for Refractory Sterility Caused by Polycystic Ovary Syndrome
摘要
Abstract
Objective To observe the clinical efficacy ofTong Yuan(short forTong Du Tiao Shen,Yin Qi Gui Yuan, referring to unblocking the Governor Vessel, regulating mind, and guiding qi back to the origin) needling method plus Letrozol and human chorionic gonadotropin (HCG) in treating refractory sterility caused by polycystic ovary syndrome (PCOS).Method Sixty clomiphene citrate-resistant PCOS-induced sterility patients were recruited and randomized into two groups. The treatment group was intervened byTong Yuanneedling plus Letrozol and HCG, while the control group was intervened only by Letrozol and HCG, both for 3 months. Prior to and after the treatment,the levels of estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) were detected; the endometrium, ovulation and pregnancy rates were also observed.Result After 3 menstrual cycles, the level of FSH increasedsignificantly (P<0.05), LH decreased significantly (P<0.05), LH/FSH declined significantly (P<0.05), and the level of T also dropped significantly (P<0.05) in both treatment group and control group; the level of E2also dropped significantly after the treatment in both groups (P<0.05), and the decrease in the treatment group was more significantly than that in the control group (P<0.05). The ovulation and pregnancy rates in the treatment group were significantly higher than those in the control group (P<0.05).Conclusion Tong Yuanneedling plus Letrozol and HCG can significantly down-regulate the levels of LH, E2and T, up-regulate the level of FSH, effectively improve the internal reproductive environment of refractory PCOS patients, and enhance the ovulation and pregnancy rates.关键词
针刺/通元针法/来曲唑/HCG/多囊卵巢综合征/不孕症/不育,女性/针药并用Key words
Acupuncture/Tong Yuanneedling/Letrozol/HCG/Polycystic ovary syndrome/Sterility/Infertility,Female/Acupuncturemedication combined分类
医药卫生引用本文复制引用
陈雨婷,李月梅,罗蛟龙,陈雨佳,郑淑珍..通元针法联合药物治疗顽固性多囊卵巢综合征不孕临床观察[J].上海针灸杂志,2017,36(6):692-696,5.基金项目
全国第5批名老中医传承工作室建设项目(201420) （201420）
